Drug Trials

View Drug Trial ID Treatment Species Trial Type Finding Descriptor +/- Frequency Value Value Units Synonyms
View 165 NIMESULIDE Human Clinical Liver :: biopsy :: Cholestasis increased Pos 0.01 - < 0.1% SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 5 VALPROIC ACID Human Clinical Liver :: Clinical Chemistry :: Hepatic Necrosis uncommon -> frequency Pos 1 - < 10% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 5 VALPROIC ACID Human Clinical Liver :: Clinical Chemistry :: Inflammation uncommon -> frequency Pos 1 - < 10% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 5 VALPROIC ACID Human Clinical Liver :: biopsy :: Cholestasis uncommon -> frequency Pos 1 - < 10% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 5 VALPROIC ACID Human Clinical Liver :: biopsy :: Fibrosis uncommon -> frequency Pos 1 - < 10% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 5 VALPROIC ACID Human Clinical Liver :: Clinical Chemistry :: Hepatocellular Damage common -> frequency Pos 1 - < 10% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 15 METHOTREXATE Human Unknown / Unspecified Liver :: biopsy :: Steatosis/Fatty Liver Pos >= 10% TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 15 METHOTREXATE Human Unknown / Unspecified Liver :: biopsy :: Fibrosis Pos >= 10% TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 7 FLUTAMIDE Human Unknown / Unspecified Liver :: biopsy :: Cholestasis uncommon -> frequency Pos 1 - < 10% SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 7 FLUTAMIDE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Mixed Type Damage uncommon -> frequency Pos 1 - < 10% SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 7 FLUTAMIDE Human Unknown / Unspecified Immune :: Other :: Hypersensitivity rare -> frequency Pos 0.1 - < 1% SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 15 METHOTREXATE Human Unknown / Unspecified Liver :: biopsy :: Cirrhosis rare -> frequency Pos 0.1 - < 1% TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 18 BOSENTAN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage common -> frequency Pos >= 10% Tracleer, Ro-47-0203-029, Bosentan, Ro-470203029
View 18 BOSENTAN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Mixed Type Damage uncommon -> frequency Pos 1 - < 10% Tracleer, Ro-47-0203-029, Bosentan, Ro-470203029
View 23 KETOCONAZOLE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage common -> frequency Pos >= 10% Xolegel, SID50104730, SID11112822, SID90341325, Extina, Ketoconazole, Ketosidin, SID50104728, SID26719656, SID124882654, Nizoral A-D, SID11113916, Ketozole, SID50104729, SID124882653, SID11533029, SID26752071, SID11111347, SID26752070, R-41400, SID85267857, Nizoral, Panfungol, SID56422892, SID50104731
View 23 KETOCONAZOLE Human Unknown / Unspecified Liver :: biopsy :: Cholestasis uncommon -> frequency Pos 1 - < 10% Xolegel, SID50104730, SID11112822, SID90341325, Extina, Ketoconazole, Ketosidin, SID50104728, SID26719656, SID124882654, Nizoral A-D, SID11113916, Ketozole, SID50104729, SID124882653, SID11533029, SID26752071, SID11111347, SID26752070, R-41400, SID85267857, Nizoral, Panfungol, SID56422892, SID50104731
View 82 NOMIFENSINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatoxicity extensive Pos 1 - < 10% Alival, SID50105261, Merital, Nomifensine, SID90340560
View 47 ACITRETIN Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage Pos >= 10% Acitretin, SID26756475, Soriatane, SID49640651, Ro-10-1670-000, SID29216416, Etretin, Ro-101670000
View 47 ACITRETIN Human Post-marketing Liver :: biopsy :: Cholestasis Pos 1 - < 10% Acitretin, SID26756475, Soriatane, SID49640651, Ro-10-1670-000, SID29216416, Etretin, Ro-101670000
View 64 AMITRIPTYLINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% Amitriptyline, Limbitrol, Endep, Amitril, Etrafon-A, Elavil, Tryptanol, SID11110782, Amitid, Etrafon-Forte, SID90340850, SID11110783, AmitriptylineHCl
View 5 VALPROIC ACID Human Clinical Liver :: Clinical Chemistry :: Microvesicular Steatosis uncommon -> frequency Pos 1 - < 10% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 166 ACETAMINOPHEN Rat Preclinical Liver :: Clinical Chemistry :: ALT increased females only Pos APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 30 NEVIRAPINE Human Unknown / Unspecified Liver :: biopsy :: Cholestasis common -> frequency Pos >= 10% Viramune Xr, SID26719643, Nevirapine, SID865943, Viramune, BIRG-0587, SID49718173, SID17388862
View 117 TOLCAPONE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos >= 10% Tasmar, Ro-407592, Tolcapone, SID144206516, Ro-40-7592, SID50126317
View 123 FELBAMATE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage common -> frequency Pos >= 10% SID855835, SID11113343, SID56422162, Felbamate, Felbatol, W-554, SID50104096, SID144203696, SID90340922
View 125 LEVOFLOXACIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% Levofloxacin, Iquix, RWJ-25213, DR-3355, Levaquin, Quixin, SID49665952, Floxacin, SID26719895
View 125 LEVOFLOXACIN Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos 1 - < 10% Levofloxacin, Iquix, RWJ-25213, DR-3355, Levaquin, Quixin, SID49665952, Floxacin, SID26719895
View 130 ISONIAZID Human Unknown / Unspecified Liver :: observation :: Jaundice Pos >= 10% SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 133 MONTELUKAST Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% MK-476, Singulair, Montelukast, Montelo-10
View 133 MONTELUKAST Human Unknown / Unspecified Liver :: Immunology :: Autoantibodies rare -> frequency Pos 0.1 - < 1% MK-476, Singulair, Montelukast, Montelo-10
View 135 FLUOXETINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% % Prozac, Sarafem, Symbyax, SID104171153, SID26755310, SID26751973, SID50104648, Fluoxetine, SID90341619, SID144203695, Prozac Weekly, FluoxetineHCl
View 135 FLUOXETINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% Prozac, Sarafem, Symbyax, SID104171153, SID26755310, SID26751973, SID50104648, Fluoxetine, SID90341619, SID144203695, Prozac Weekly, FluoxetineHCl
View 135 FLUOXETINE Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos 1 - < 10% Prozac, Sarafem, Symbyax, SID104171153, SID26755310, SID26751973, SID50104648, Fluoxetine, SID90341619, SID144203695, Prozac Weekly, FluoxetineHCl
View 138 SERTRALINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 0.1 - < 1% SID50105685, SID50105684, Zoloft, SID50105682, SID49665783, SID90341218, SID29215139, Sertraline, SID26753299, SID50105683
View 138 SERTRALINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% SID50105685, SID50105684, Zoloft, SID50105682, SID49665783, SID90341218, SID29215139, Sertraline, SID26753299, SID50105683
View 143 FAMOTIDINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos >= 10% Pepcid Rpd, SID85231052, SID144203704, SID26753575, Fluxid, SID11111194, Pepcid, SID50106279, SID26748463, SID11111195, MK-208, SID49681730, SID855518, Famotidine, Pepcid Ac
View 145 GABAPENTIN Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos 1 - < 10% SID90340599, SID50103936, SID11112806, SID11113327, SID104171164, Gabapentin, Neurontin, SID855579, CI-945, GOE-3450, Gralise
View 147 DIDANOSINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 147 DIDANOSINE Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos 1 - < 10% BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 151 LOVASTATIN Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos >= 10% SID17389841, SID26751557, Altoprev, SID49732779, SID855905, Lovastatin, SID496591, MK-803, Mevacor, Mevinolin, SID144204439
View 151 LOVASTATIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% SID17389841, SID26751557, Altoprev, SID49732779, SID855905, Lovastatin, SID496591, MK-803, Mevacor, Mevinolin, SID144204439
View 151 LOVASTATIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% SID17389841, SID26751557, Altoprev, SID49732779, SID855905, Lovastatin, SID496591, MK-803, Mevacor, Mevinolin, SID144204439
View 151 LOVASTATIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: ALT Pos 0.1 - < 1% SID17389841, SID26751557, Altoprev, SID49732779, SID855905, Lovastatin, SID496591, MK-803, Mevacor, Mevinolin, SID144204439
View 153 PIOGLITAZONE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% Actos, SID137275816, SID26756476, Pioglitazone, Duetact
View 160 SIMVASTATIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% MK-733, Synvinolin, Simvastatin, Simvastatin hydroxy acid, SID496592, Zocor, SID50086525, SID144204247
View 160 SIMVASTATIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% MK-733, Synvinolin, Simvastatin, Simvastatin hydroxy acid, SID496592, Zocor, SID50086525, SID144204247
View 160 SIMVASTATIN Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos 1 - < 10% MK-733, Synvinolin, Simvastatin, Simvastatin hydroxy acid, SID496592, Zocor, SID50086525, SID144204247
View 162 FLUVASTATIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Fluvastatin
View 162 FLUVASTATIN Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos 1 - < 10% Fluvastatin
View 123 FELBAMATE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Liver Function Test uncommon -> frequency Pos 1 - < 10% SID855835, SID11113343, SID56422162, Felbamate, Felbatol, W-554, SID50104096, SID144203696, SID90340922
View 130 ISONIAZID Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos >= 10% SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 130 ISONIAZID Human Unknown / Unspecified Liver :: Clinical Chemistry :: Bilirubin Pos 1 - < 10% SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 5 VALPROIC ACID Human Clinical Liver :: PK :: Cyp P450 Metabolism Pos < 0.01% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 5 VALPROIC ACID Human Clinical Liver :: PK :: Biliary elimination Pos < 0.01% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 5 VALPROIC ACID Human Clinical Kidney :: PK :: Urinary Elimination Pos < 0.01% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 5 VALPROIC ACID Human Clinical Liver :: Clinical Chemistry :: Liver Function Test Pos < 0.01% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 7 FLUTAMIDE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 10 DANTROLENE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 0.1 - < 1% F-368, SID26756482, Dantrolene, Dantamacrin, SID26756773, Dantrium, DantroleneNa
View 15 METHOTREXATE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos >= 10% TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 18 BOSENTAN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos >= 10% Tracleer, Ro-47-0203-029, Bosentan, Ro-470203029
View 23 KETOCONAZOLE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos >= 10% Xolegel, SID50104730, SID11112822, SID90341325, Extina, Ketoconazole, Ketosidin, SID50104728, SID26719656, SID124882654, Nizoral A-D, SID11113916, Ketozole, SID50104729, SID124882653, SID11533029, SID26752071, SID11111347, SID26752070, R-41400, SID85267857, Nizoral, Panfungol, SID56422892, SID50104731
View 28 NALTREXONE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos >= 10% Celupan, EN-1639A, Revia, Naltrexone, EN-1639A [As Hydrochloride], Vivitrol, Trexal, Trexan
View 30 NEVIRAPINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: ALT Pos >= 10% Viramune Xr, SID26719643, Nevirapine, SID865943, Viramune, BIRG-0587, SID49718173, SID17388862
View 47 ACITRETIN Human Post-marketing Liver :: Clinical Chemistry :: Liver Function Test Pos 1 - < 10% Acitretin, SID26756475, Soriatane, SID49640651, Ro-10-1670-000, SID29216416, Etretin, Ro-101670000
View 52 NADOLOL Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% 0.5 % Nadolol, SQ-11725, SID855594, SID56422422, Corgard
View 7 FLUTAMIDE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos >= 10% SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 10 DANTROLENE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% F-368, SID26756482, Dantrolene, Dantamacrin, SID26756773, Dantrium, DantroleneNa
View 40 ATENOLOL Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Esatenolol, Unibloc, SID50104387, Tenormin, ICI-66082, SID90340978, SID855957, SID26751696, Atenolol, SID50085956, Ibinolo
View 46 DESIPRAMINE Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos >= 10% Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 64 AMITRIPTYLINE Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos >= 10% Amitriptyline, Limbitrol, Endep, Amitril, Etrafon-A, Elavil, Tryptanol, SID11110782, Amitid, Etrafon-Forte, SID90340850, SID11110783, AmitriptylineHCl
View 70 PAROXETINE Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% BRL-29060, Paroxetine, Paxil, SID50104981, SID26752262, SID144206674, SID50104978, SID50104979, SID50104980, SID29215051, SID90341371, Paxil [as hydrochloride], Pexeva
View 73 ROFECOXIB Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 75 ROFECOXIB Human Post-marketing Liver :: Clinical Chemistry :: ALT Pos >= 10% Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 75 ROFECOXIB Human Post-marketing Liver :: Clinical Chemistry :: Liver Function Test Pos < 0.01% Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 28 NALTREXONE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Celupan, EN-1639A, Revia, Naltrexone, EN-1639A [As Hydrochloride], Vivitrol, Trexal, Trexan
View 55 ASPIRIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos >= 10% Acetosalic Acid, Acetylsalicylic Acid, SID87798, SID17390036, Measurin, Ecotrin, SID85230910, SID26752858, 8-Hour Bayer, Salicylic Acid Acetate, SID90340586, SID47193676, SID17389202, Aspirin, Bayer Extra Strength, Equi-Prin, SID26747283, SID50105490, Acetylsalicylic acid
View 162 FLUVASTATIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Fluvastatin
View 173 NEFAZODONE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage increased Pos 1 - < 10% Nefazodone, Serzone, SID50111710, SID49666410, Nefadar, Nefazodone Hydrochloride
View 173 NEFAZODONE Human Post-marketing Liver :: Clinical Chemistry :: Hepatic Necrosis increased Pos 0.1 - < 1% Nefazodone, Serzone, SID50111710, SID49666410, Nefadar, Nefazodone Hydrochloride
View 173 NEFAZODONE Human Post-marketing Immune :: Other :: Hypersensitivity increased Pos 0.1 - < 1% Nefazodone, Serzone, SID50111710, SID49666410, Nefadar, Nefazodone Hydrochloride
View 173 NEFAZODONE Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos 1 - < 10% Nefazodone, Serzone, SID50111710, SID49666410, Nefadar, Nefazodone Hydrochloride
View 7 FLUTAMIDE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage common -> frequency Pos >= 10% SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 83 GEFITINIB Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos >= 10% SID50100103, SID137275808, ZDJ-839, Gefitinib, SID29215403, SID144205236, SID103905344, SID103905343, Iressa, ZD-1839
View 83 GEFITINIB Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% SID50100103, SID137275808, ZDJ-839, Gefitinib, SID29215403, SID144205236, SID103905344, SID103905343, Iressa, ZD-1839
View 93 GREPAFLOXACIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos >= 10% Grepafloxacin, SID50112780, Raxar, Vaxor
View 98 CYCLOPHOSPHAMIDE Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos >= 10% SID90341534, SID87150, Cyclophosphamide, Neosar, SID85230959, SID50105634, Sendoxan, Cytoxan
View 108 PERGOLIDE Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos < 0.01% Pergolide, Pergotoliderived, SID104171354, SID26754330, SID26754331, SID90341767, Permax
View 30 NEVIRAPINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Viramune Xr, SID26719643, Nevirapine, SID865943, Viramune, BIRG-0587, SID49718173, SID17388862
View 30 NEVIRAPINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 0.1 - < 1% Viramune Xr, SID26719643, Nevirapine, SID865943, Viramune, BIRG-0587, SID49718173, SID17388862
View 125 LEVOFLOXACIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Levofloxacin, Iquix, RWJ-25213, DR-3355, Levaquin, Quixin, SID49665952, Floxacin, SID26719895
View 96 BLEOMYCIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos >= 10% Blenoxane, Bleomycin sulfate
View 96 BLEOMYCIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos 1 - < 10% 500.0 % Blenoxane, Bleomycin sulfate
View 121 BUSPIRONE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases increased Pos 1 - < 10% Buspar, SID11110857, SID11112732, SID26751994, SID11113821, Buspirone, SID90340780, SID104171117, BuspironeHCl
View 35 FLUVASTATIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos 1 - < 10% Fluvastatin
View 35 FLUVASTATIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos 1 - < 10% 300.0 % Fluvastatin
View 5 VALPROIC ACID Human Clinical Liver :: Clinical Chemistry :: Mitochondrial Toxicity likely Pos 1 - < 10% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 15 METHOTREXATE Human Unknown / Unspecified Liver :: biopsy :: Fibrosis Pos >= 10% TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 10 DANTROLENE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage common -> frequency Pos >= 10% F-368, SID26756482, Dantrolene, Dantamacrin, SID26756773, Dantrium, DantroleneNa
View 23 KETOCONAZOLE Human Unknown / Unspecified Immune :: Other :: Hypersensitivity rare -> frequency Pos 0.1 - < 1% Xolegel, SID50104730, SID11112822, SID90341325, Extina, Ketoconazole, Ketosidin, SID50104728, SID26719656, SID124882654, Nizoral A-D, SID11113916, Ketozole, SID50104729, SID124882653, SID11533029, SID26752071, SID11111347, SID26752070, R-41400, SID85267857, Nizoral, Panfungol, SID56422892, SID50104731
View 64 AMITRIPTYLINE Human Post-marketing Liver :: biopsy :: Cholestasis Pos 1 - < 10% Amitriptyline, Limbitrol, Endep, Amitril, Etrafon-A, Elavil, Tryptanol, SID11110782, Amitid, Etrafon-Forte, SID90340850, SID11110783, AmitriptylineHCl
View 30 NEVIRAPINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos 1 - < 10% Viramune Xr, SID26719643, Nevirapine, SID865943, Viramune, BIRG-0587, SID49718173, SID17388862
View 130 ISONIAZID Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos >= 10% SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 133 MONTELUKAST Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos 1 - < 10% MK-476, Singulair, Montelukast, Montelo-10
View 138 SERTRALINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% SID50105685, SID50105684, Zoloft, SID50105682, SID49665783, SID90341218, SID29215139, Sertraline, SID26753299, SID50105683
View 143 FAMOTIDINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Pepcid Rpd, SID85231052, SID144203704, SID26753575, Fluxid, SID11111194, Pepcid, SID50106279, SID26748463, SID11111195, MK-208, SID49681730, SID855518, Famotidine, Pepcid Ac
View 147 DIDANOSINE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatocellular Damage Pos 1 - < 10% BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 153 PIOGLITAZONE Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos 1 - < 10% Actos, SID137275816, SID26756476, Pioglitazone, Duetact
View 160 SIMVASTATIN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% MK-733, Synvinolin, Simvastatin, Simvastatin hydroxy acid, SID496592, Zocor, SID50086525, SID144204247
View 130 ISONIAZID Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 5 VALPROIC ACID Human Clinical Liver :: Clinical Chemistry :: Bilirubin Pos 1 - < 10% SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 7 FLUTAMIDE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 18 BOSENTAN Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Tracleer, Ro-47-0203-029, Bosentan, Ro-470203029
View 47 ACITRETIN Human Post-marketing Liver :: Clinical Chemistry :: ALT Pos >= 10% 45.0 IU/L Acitretin, SID26756475, Soriatane, SID49640651, Ro-10-1670-000, SID29216416, Etretin, Ro-101670000
View 15 METHOTREXATE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 43 PROPRANOLOL Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Propranolol, SID26751802, Inderide-40/25, SID124881056, Innopran Xl, Inderal, SID50104497, Inderide-80/25, SID90341556, SID26755283
View 74 CIMETIDINE Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% SID17389962, Cimetidine, Valmagen, SID104171130, SID11113773, SID90341189, SID26751957, SID50104629, SID460110, SID11533056, SID56462993, Brumetadina, Tagamet HB, SID26747359, Tagamet, Tagamet HB 200
View 117 TOLCAPONE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos 1 - < 10% Tasmar, Ro-407592, Tolcapone, SID144206516, Ro-40-7592, SID50126317
View 110 CIPROFLOXACIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos 1 - < 10% BAY-Q-3939, Ciloxan, Ciprobay, Velmonit, SID11112875, SID26748814, Cipro, Ciprofloxacin, SID124882697
View 172 TROGLITAZONE Human Clinical Liver :: Clinical Chemistry :: ALT increased Pos 1 - < 10% 1.9 % Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 172 TROGLITAZONE Human Clinical Liver :: Clinical Chemistry :: AST increased Pos 0.01 - < 0.1% 0.5 % Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 165 NIMESULIDE Human Clinical Liver :: Clinical Chemistry :: Liver Function Test increased Pos 1 - < 10% 1.0 % SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 5 VALPROIC ACID Human Clinical Blood :: PK :: Plasma Protein Binding Pos < 0.01% 90.0 % SID26752921, SID90341449, Depakene, Valproic Acid, Valproic acid, SID399407, Stavzor, SID17389523, 44089, Valproate
View 7 FLUTAMIDE Human Unknown / Unspecified Liver :: mechanism :: Reactive Intermediate Pos SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 10 DANTROLENE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Hepatic Necrosis Pos F-368, SID26756482, Dantrolene, Dantamacrin, SID26756773, Dantrium, DantroleneNa
View 10 DANTROLENE Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos F-368, SID26756482, Dantrolene, Dantamacrin, SID26756773, Dantrium, DantroleneNa
View 10 DANTROLENE Human Unknown / Unspecified Immune :: Other :: Hypersensitivity Pos F-368, SID26756482, Dantrolene, Dantamacrin, SID26756773, Dantrium, DantroleneNa
View 10 DANTROLENE Human Unknown / Unspecified Liver :: mechanism :: Reactive Intermediate Pos F-368, SID26756482, Dantrolene, Dantamacrin, SID26756773, Dantrium, DantroleneNa
View 21 BOSENTAN Rat Preclinical Liver :: Clinical Chemistry :: Liver Weight Pos Tracleer, Ro-47-0203-029, Bosentan, Ro-470203029
View 21 BOSENTAN Rat Preclinical Liver :: Clinical Chemistry :: No Finding Pos Tracleer, Ro-47-0203-029, Bosentan, Ro-470203029
View 30 NEVIRAPINE Human Unknown / Unspecified Immune :: Other :: Hypersensitivity Pos Viramune Xr, SID26719643, Nevirapine, SID865943, Viramune, BIRG-0587, SID49718173, SID17388862
View 48 DESIPRAMINE Human Clinical Liver :: mechanism :: Reactive Intermediate Pos Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 46 DESIPRAMINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 46 DESIPRAMINE Human Post-marketing Liver :: biopsy :: Cholestasis uncommon -> frequency Pos Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 46 DESIPRAMINE Human Post-marketing Immune :: Other :: Hypersensitivity common -> frequency Pos Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 46 DESIPRAMINE Human Post-marketing Liver :: Immunology :: Autoantibodies rare -> frequency Pos Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 56 ROSIGLITAZONE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos Avandaryl, Avandia, Rosiglitazone, SID26748954, SID144204987, Avandamet, BRL-49653
View 60 CISPLATIN Human Post-marketing Liver :: biopsy :: Steatosis/Fatty Liver increased Pos SID557830, SID50105439, CIS-DDP, SID301178, Cis-Platinum II, SID90340859, SID17389100, Platinol, Cisplatin
View 60 CISPLATIN Human Post-marketing Liver :: Clinical Chemistry :: Hepatic Necrosis increased Pos SID557830, SID50105439, CIS-DDP, SID301178, Cis-Platinum II, SID90340859, SID17389100, Platinol, Cisplatin
View 64 AMITRIPTYLINE Human Post-marketing Immune :: Other :: Hypersensitivity Pos Amitriptyline, Limbitrol, Endep, Amitril, Etrafon-A, Elavil, Tryptanol, SID11110782, Amitid, Etrafon-Forte, SID90340850, SID11110783, AmitriptylineHCl
View 64 AMITRIPTYLINE Human Post-marketing Liver :: Clinical Chemistry :: Haptotype Pos Amitriptyline, Limbitrol, Endep, Amitril, Etrafon-A, Elavil, Tryptanol, SID11110782, Amitid, Etrafon-Forte, SID90340850, SID11110783, AmitriptylineHCl
View 70 PAROXETINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos BRL-29060, Paroxetine, Paxil, SID50104981, SID26752262, SID144206674, SID50104978, SID50104979, SID50104980, SID29215051, SID90341371, Paxil [as hydrochloride], Pexeva
View 70 PAROXETINE Human Post-marketing Liver :: biopsy :: Cholestasis uncommon -> frequency Pos BRL-29060, Paroxetine, Paxil, SID50104981, SID26752262, SID144206674, SID50104978, SID50104979, SID50104980, SID29215051, SID90341371, Paxil [as hydrochloride], Pexeva
View 73 ROFECOXIB Human Post-marketing Liver :: biopsy :: Cholestasis uncommon -> frequency Pos Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 73 ROFECOXIB Human Post-marketing Immune :: Other :: Hypersensitivity uncommon -> frequency Pos Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 74 CIMETIDINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos SID17389962, Cimetidine, Valmagen, SID104171130, SID11113773, SID90341189, SID26751957, SID50104629, SID460110, SID11533056, SID56462993, Brumetadina, Tagamet HB, SID26747359, Tagamet, Tagamet HB 200
View 74 CIMETIDINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatic Necrosis Pos SID17389962, Cimetidine, Valmagen, SID104171130, SID11113773, SID90341189, SID26751957, SID50104629, SID460110, SID11533056, SID56462993, Brumetadina, Tagamet HB, SID26747359, Tagamet, Tagamet HB 200
View 74 CIMETIDINE Human Post-marketing Immune :: Other :: Hypersensitivity uncommon -> frequency Pos SID17389962, Cimetidine, Valmagen, SID104171130, SID11113773, SID90341189, SID26751957, SID50104629, SID460110, SID11533056, SID56462993, Brumetadina, Tagamet HB, SID26747359, Tagamet, Tagamet HB 200
View 75 ROFECOXIB Human Post-marketing Liver :: Clinical Chemistry :: Hepatoxicity rare -> frequency Pos Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 75 ROFECOXIB Human Post-marketing Liver :: observation :: Jaundice rare -> frequency Pos Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 76 ROFECOXIB Rat Post-marketing Liver :: Clinical Chemistry :: No Finding Neg Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 77 ROFECOXIB Dog Post-marketing Liver :: Clinical Chemistry :: No Finding Neg Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 78 CISAPRIDE Human Post-marketing Liver :: biopsy :: Cholestasis reversible Pos Propulsid, Cisapride, Risamal, R-51619, SID144204250, Acenalin
View 80 TEMAFLOXACIN Human Clinical Liver :: Clinical Chemistry :: No Finding Neg Omniflox, Temafloxacin, Temac
View 81 CHLORZOXAZONE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos Strifon Forte Dsc, Parafon Forte, Chlorzoxazone, Parafon Forte Dsc, Paraflex, SID11110946, Parafon, Strifon, Parafon-Forte, SID11110945
View 81 CHLORZOXAZONE Human Post-marketing Immune :: Other :: Hypersensitivity Pos Strifon Forte Dsc, Parafon Forte, Chlorzoxazone, Parafon Forte Dsc, Paraflex, SID11110946, Parafon, Strifon, Parafon-Forte, SID11110945
View 83 GEFITINIB Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage Pos SID50100103, SID137275808, ZDJ-839, Gefitinib, SID29215403, SID144205236, SID103905344, SID103905343, Iressa, ZD-1839
View 87 SIBUTRAMINE Human Post-marketing Liver :: biopsy :: Cholestasis uncommon -> frequency Pos Sibutramine, Meridia, SID49732001
View 89 CERIVASTATIN Human Post-marketing Liver :: Clinical Chemistry :: Hepatoxicity common -> frequency Pos SID50111694, Cerivastatin, Lipobay, Baycol
View 90 TERFENADINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos Triludan, SID144203846, Seldane, RMI-9918, SID90341346, SID56422373, SID85231279, Terfenadine, SID26752308, SID855647, Teldane, SID104171258, SID144203847, SID50105228
View 92 PAROXETINE Dog Post-marketing Liver :: Clinical Chemistry :: No Finding Neg BRL-29060, Paroxetine, Paxil, SID50104981, SID26752262, SID144206674, SID50104978, SID50104979, SID50104980, SID29215051, SID90341371, Paxil [as hydrochloride], Pexeva
View 94 GREPAFLOXACIN Rat Post-marketing Liver :: Clinical Chemistry :: No Finding Pos Grepafloxacin, SID50112780, Raxar, Vaxor
View 95 GREPAFLOXACIN Dog Post-marketing Liver :: Clinical Chemistry :: No Finding Pos Grepafloxacin, SID50112780, Raxar, Vaxor
View 98 CYCLOPHOSPHAMIDE Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos SID90341534, SID87150, Cyclophosphamide, Neosar, SID85230959, SID50105634, Sendoxan, Cytoxan
View 102 GENTAMICIN Human Post-marketing Liver :: biopsy :: Cholestasis uncommon -> frequency Pos Genoptic, Bristagen, SCH-9724, Apogen, Garacin, Gentacidin, Gentak, Uromycine, Gentafair, Gentamicin, U-Gencin
View 102 GENTAMICIN Human Post-marketing Immune :: Other :: Hypersensitivity uncommon -> frequency Pos Genoptic, Bristagen, SCH-9724, Apogen, Garacin, Gentacidin, Gentak, Uromycine, Gentafair, Gentamicin, U-Gencin
View 106 PRIMAQUINE Human Post-marketing Liver :: Clinical Chemistry :: No Liver Effects Neg Primaquine, SID24715073, SID24715072
View 106 PRIMAQUINE Human Post-marketing Liver :: observation :: Jaundice Pos Primaquine, SID24715073, SID24715072
View 110 CIPROFLOXACIN Human Post-marketing Liver :: Clinical Chemistry :: Hepatocellular Damage uncommon -> frequency Pos BAY-Q-3939, Ciloxan, Ciprobay, Velmonit, SID11112875, SID26748814, Cipro, Ciprofloxacin, SID124882697
View 110 CIPROFLOXACIN Human Post-marketing Liver :: biopsy :: Cholestasis uncommon -> frequency Pos BAY-Q-3939, Ciloxan, Ciprobay, Velmonit, SID11112875, SID26748814, Cipro, Ciprofloxacin, SID124882697
View 110 CIPROFLOXACIN Human Post-marketing Immune :: Other :: Hypersensitivity Pos BAY-Q-3939, Ciloxan, Ciprobay, Velmonit, SID11112875, SID26748814, Cipro, Ciprofloxacin, SID124882697
View 116 TOLCAPONE Human Post-marketing Liver :: observation :: Jaundice Pos Tasmar, Ro-407592, Tolcapone, SID144206516, Ro-40-7592, SID50126317
View 116 TOLCAPONE Human Post-marketing Liver :: Clinical Chemistry :: Hepatitis Pos Tasmar, Ro-407592, Tolcapone, SID144206516, Ro-40-7592, SID50126317
View 123 FELBAMATE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Inflammation Pos SID855835, SID11113343, SID56422162, Felbamate, Felbatol, W-554, SID50104096, SID144203696, SID90340922
View 130 ISONIAZID Human Unknown / Unspecified Immune :: Other :: Hypersensitivity Pos SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 133 MONTELUKAST Human Unknown / Unspecified Liver :: Clinical Chemistry :: Transaminases Pos MK-476, Singulair, Montelukast, Montelo-10
View 138 SERTRALINE Human Unknown / Unspecified Liver :: biopsy :: Cholestasis Pos SID50105685, SID50105684, Zoloft, SID50105682, SID49665783, SID90341218, SID29215139, Sertraline, SID26753299, SID50105683
View 147 DIDANOSINE Human Unknown / Unspecified Liver :: biopsy :: Steatosis/Fatty Liver Pos BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 148 DIDANOSINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatoxicity Pos BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 148 DIDANOSINE Human Post-marketing Liver :: Clinical Chemistry :: Hepatitis Pos BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 148 DIDANOSINE Human Post-marketing Liver :: biopsy :: Steatosis/Fatty Liver Pos BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 130 ISONIAZID Human Unknown / Unspecified Liver :: Immunology :: Autoantibodies Pos SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 15 METHOTREXATE Human Unknown / Unspecified Liver :: Clinical Chemistry :: ALT Pos TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 18 BOSENTAN Human Unknown / Unspecified Liver :: PK :: Induction Pos Tracleer, Ro-47-0203-029, Bosentan, Ro-470203029
View 18 BOSENTAN Human Unknown / Unspecified Liver :: PK :: Cyp P450 Metabolism Pos Tracleer, Ro-47-0203-029, Bosentan, Ro-470203029
View 30 NEVIRAPINE Human Unknown / Unspecified Liver :: PK :: Induction Pos Viramune Xr, SID26719643, Nevirapine, SID865943, Viramune, BIRG-0587, SID49718173, SID17388862
View 55 ASPIRIN Human Post-marketing Liver :: Clinical Chemistry :: Alkaline Phosphatase Pos Acetosalic Acid, Acetylsalicylic Acid, SID87798, SID17390036, Measurin, Ecotrin, SID85230910, SID26752858, 8-Hour Bayer, Salicylic Acid Acetate, SID90340586, SID47193676, SID17389202, Aspirin, Bayer Extra Strength, Equi-Prin, SID26747283, SID50105490, Acetylsalicylic acid
View 55 ASPIRIN Human Post-marketing Liver :: Clinical Chemistry :: Bilirubin Pos Acetosalic Acid, Acetylsalicylic Acid, SID87798, SID17390036, Measurin, Ecotrin, SID85230910, SID26752858, 8-Hour Bayer, Salicylic Acid Acetate, SID90340586, SID47193676, SID17389202, Aspirin, Bayer Extra Strength, Equi-Prin, SID26747283, SID50105490, Acetylsalicylic acid
View 60 CISPLATIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos SID557830, SID50105439, CIS-DDP, SID301178, Cis-Platinum II, SID90340859, SID17389100, Platinol, Cisplatin
View 70 PAROXETINE Human Post-marketing Liver :: Clinical Chemistry :: Transaminases Pos BRL-29060, Paroxetine, Paxil, SID50104981, SID26752262, SID144206674, SID50104978, SID50104979, SID50104980, SID29215051, SID90341371, Paxil [as hydrochloride], Pexeva
View 75 ROFECOXIB Human Post-marketing Liver :: PK :: Cyp P450 inhibition Pos Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 75 ROFECOXIB Human Post-marketing Systemic :: PK :: Bioavailability Pos 93.0 % Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 75 ROFECOXIB Human Post-marketing Blood :: PK :: Plasma Protein Binding Pos 85.0 % Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 55 ASPIRIN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos Acetosalic Acid, Acetylsalicylic Acid, SID87798, SID17390036, Measurin, Ecotrin, SID85230910, SID26752858, 8-Hour Bayer, Salicylic Acid Acetate, SID90340586, SID47193676, SID17389202, Aspirin, Bayer Extra Strength, Equi-Prin, SID26747283, SID50105490, Acetylsalicylic acid
View 166 ACETAMINOPHEN Rat Preclinical Liver :: Clinical Chemistry :: AST increased females only Pos APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 166 ACETAMINOPHEN Rat Preclinical Liver :: Clinical Chemistry :: Alkaline Phosphatase increased females only Pos APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 166 ACETAMINOPHEN Rat Preclinical Liver :: Clinical Chemistry :: Bilirubin increased females only Pos APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 171 CAFFEINE Human Unknown / Unspecified None :: Other :: Fatal Pos 57.0 mg/kg Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 173 NEFAZODONE Human Post-marketing Liver :: mechanism :: Reactive Intermediate likely Pos Nefazodone, Serzone, SID50111710, SID49666410, Nefadar, Nefazodone Hydrochloride
View 75 ROFECOXIB Human Post-marketing Kidney :: PK :: Urinary Elimination Pos 72.0 % Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 75 ROFECOXIB Human Post-marketing Liver :: PK :: Biliary elimination Pos 14.0 % Rofecoxib, SID26748942, SID49665949, Vioxx, MK-0966, MK-966, SID535364
View 78 CISAPRIDE Human Post-marketing Systemic :: PK :: Bioavailability Pos 45.0 % Propulsid, Cisapride, Risamal, R-51619, SID144204250, Acenalin
View 78 CISAPRIDE Human Post-marketing Liver :: PK :: Biliary elimination Pos 50.0 % Propulsid, Cisapride, Risamal, R-51619, SID144204250, Acenalin
View 78 CISAPRIDE Human Post-marketing Kidney :: PK :: Urinary Elimination Pos 50.0 % Propulsid, Cisapride, Risamal, R-51619, SID144204250, Acenalin
View 78 CISAPRIDE Human Post-marketing Blood :: PK :: Plasma Protein Binding Pos 97.5 % Propulsid, Cisapride, Risamal, R-51619, SID144204250, Acenalin
View 79 PHENYLBUTAZONE Human Post-marketing Liver :: PK :: Cyp P450 inhibition Pos 80.0 % Elmedal, SID144203794, Pro-Bute, Azolid, SID17389760, Diphenylbutazone, Equiphar, SID50104199, SID85231197, Butaject, SID56436656, SID104171221, Butazolidin, Phenylbutazone, Antadol, SID855958, SID11111674, SID26751573, SID26747057, SID104171220, SID90341773
View 79 PHENYLBUTAZONE Human Post-marketing Blood :: PK :: Plasma Protein Binding Pos 90.0 % Elmedal, SID144203794, Pro-Bute, Azolid, SID17389760, Diphenylbutazone, Equiphar, SID50104199, SID85231197, Butaject, SID56436656, SID104171221, Butazolidin, Phenylbutazone, Antadol, SID855958, SID11111674, SID26751573, SID26747057, SID104171220, SID90341773
View 79 PHENYLBUTAZONE Human Post-marketing Liver :: PK :: Biliary elimination Pos 10.0 % Elmedal, SID144203794, Pro-Bute, Azolid, SID17389760, Diphenylbutazone, Equiphar, SID50104199, SID85231197, Butaject, SID56436656, SID104171221, Butazolidin, Phenylbutazone, Antadol, SID855958, SID11111674, SID26751573, SID26747057, SID104171220, SID90341773
View 79 PHENYLBUTAZONE Human Post-marketing Kidney :: PK :: Urinary Elimination Pos 90.0 % Elmedal, SID144203794, Pro-Bute, Azolid, SID17389760, Diphenylbutazone, Equiphar, SID50104199, SID85231197, Butaject, SID56436656, SID104171221, Butazolidin, Phenylbutazone, Antadol, SID855958, SID11111674, SID26751573, SID26747057, SID104171220, SID90341773
View 88 SIBUTRAMINE Human Post-marketing Systemic :: PK :: Bioavailability Pos 24.0 % Sibutramine, Meridia, SID49732001
View 88 SIBUTRAMINE Human Post-marketing Blood :: PK :: Plasma Protein Binding Pos 97.0 % Sibutramine, Meridia, SID49732001
View 89 CERIVASTATIN Human Post-marketing Systemic :: PK :: Bioavailability Pos 60.0 % SID50111694, Cerivastatin, Lipobay, Baycol
View 89 CERIVASTATIN Human Post-marketing Liver :: PK :: Biliary elimination Pos 70.0 % SID50111694, Cerivastatin, Lipobay, Baycol
View 74 CIMETIDINE Human Post-marketing Liver :: biopsy :: Cholestasis uncommon -> frequency Pos SID17389962, Cimetidine, Valmagen, SID104171130, SID11113773, SID90341189, SID26751957, SID50104629, SID460110, SID11533056, SID56462993, Brumetadina, Tagamet HB, SID26747359, Tagamet, Tagamet HB 200
View 89 CERIVASTATIN Human Post-marketing Kidney :: PK :: Urinary Elimination Pos 30.0 % SID50111694, Cerivastatin, Lipobay, Baycol
View 90 TERFENADINE Human Post-marketing Liver :: Clinical Chemistry :: Liver Function Test Neg Triludan, SID144203846, Seldane, RMI-9918, SID90341346, SID56422373, SID85231279, Terfenadine, SID26752308, SID855647, Teldane, SID104171258, SID144203847, SID50105228
View 91 TERFENADINE Human Post-marketing Systemic :: PK :: Bioavailability Pos 1.0 % Triludan, SID144203846, Seldane, RMI-9918, SID90341346, SID56422373, SID85231279, Terfenadine, SID26752308, SID855647, Teldane, SID104171258, SID144203847, SID50105228
View 93 GREPAFLOXACIN Human Post-marketing Kidney :: PK :: Urinary Elimination Pos 12.6 % Grepafloxacin, SID50112780, Raxar, Vaxor
View 93 GREPAFLOXACIN Human Post-marketing Liver :: PK :: Biliary elimination Pos 31.5 % Grepafloxacin, SID50112780, Raxar, Vaxor
View 102 GENTAMICIN Human Post-marketing Liver :: Clinical Chemistry :: Alkaline Phosphatase Pos Genoptic, Bristagen, SCH-9724, Apogen, Garacin, Gentacidin, Gentak, Uromycine, Gentafair, Gentamicin, U-Gencin
View 117 TOLCAPONE Human Unknown / Unspecified Liver :: Clinical Chemistry :: Glucuronidation Pos Tasmar, Ro-407592, Tolcapone, SID144206516, Ro-40-7592, SID50126317
View 60 CISPLATIN Human Post-marketing Liver :: Clinical Chemistry :: Hepatoxicity rare -> frequency Pos SID557830, SID50105439, CIS-DDP, SID301178, Cis-Platinum II, SID90340859, SID17389100, Platinol, Cisplatin
View 46 DESIPRAMINE Human Post-marketing Liver :: Clinical Chemistry :: Liver Function Test abnormal Pos Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 169 NIMESULIDE Rat Preclinical None :: Other :: LD50 Oral Pos 200.0 mg/kg SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 174 ENTACAPONE Human Clinical Liver :: Clinical Chemistry :: Glucuronidation increased Pos Comtan, Entacapone, OR-611, SID26757974
View 174 ENTACAPONE Human Clinical Liver :: PK :: Cyp P450 Metabolism extensive Pos Comtan, Entacapone, OR-611, SID26757974
View 174 ENTACAPONE Human Clinical Systemic :: PK :: Bioavailability Pos 29.0 % Comtan, Entacapone, OR-611, SID26757974
View 174 ENTACAPONE Human Clinical None :: PK :: Protein Binding extensive Pos 98.0 % Comtan, Entacapone, OR-611, SID26757974
View 172 TROGLITAZONE Human Clinical Systemic :: PK :: Bioavailability Pos 50.0 % Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 172 TROGLITAZONE Human Clinical Liver :: Clinical Chemistry :: Glucuronidation Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 172 TROGLITAZONE Human Clinical Liver :: mechanism :: Reactive Intermediate Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 172 TROGLITAZONE Human Clinical Liver :: PK :: Sulfation Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 172 TROGLITAZONE Human Clinical Blood :: PK :: Cmax Pos 2.82 µg/mL Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 174 ENTACAPONE Human Clinical Blood :: PK :: Cmax Pos 1.22 µg/mL Comtan, Entacapone, OR-611, SID26757974
View 178 TOLCAPONE Human Clinical Blood :: PK :: Cmax Pos 7.2 µg/mL Tasmar, Ro-407592, Tolcapone, SID144206516, Ro-40-7592, SID50126317
View 177 ENTACAPONE Dog Preclinical Multiple Organs :: Other :: No Toxicity Neg Comtan, Entacapone, OR-611, SID26757974
View 176 ENTACAPONE Rat Preclinical Multiple Organs :: Other :: No Toxicity Neg Comtan, Entacapone, OR-611, SID26757974
View 179 TROGLITAZONE Human Post-marketing None :: Other :: Fatal Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 179 TROGLITAZONE Human Post-marketing Liver :: Clinical Chemistry :: Hepatic Necrosis Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 179 TROGLITAZONE Human Post-marketing Liver :: Clinical Chemistry :: Inflammation Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 179 TROGLITAZONE Human Post-marketing Liver :: mechanism :: Reactive Intermediate Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 180 TROGLITAZONE Rat Preclinical Liver :: Clinical Chemistry :: Liver Weight increased Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 180 TROGLITAZONE Rat Preclinical Systemic :: Hematology :: RBC, HGB, HCT decreased Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 171 CAFFEINE Human Unknown / Unspecified Blood :: PK :: T1/2 Pos 4.2 hours Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 181 CAFFEINE Human Post-marketing Heart :: observation :: Cardiac Arrhythmia increased Pos Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 182 CAFFEINE Rat Preclinical Systemic :: Other :: Body Weights decreased Pos Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 182 CAFFEINE Rat Preclinical Multiple Organs :: Other :: No Toxicity Pos Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 182 CAFFEINE Rat Preclinical Systemic :: observation :: NOAEL male Pos 151.0 mg/kg/day Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 182 CAFFEINE Rat Preclinical Systemic :: observation :: NOAEL female Pos 174.0 mg/kg/day Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 183 CAFFEINE Human Clinical Systemic :: PK :: Bioavailability well absorbed Pos Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 183 CAFFEINE Human Clinical Kidney :: PK :: Renal Clearance extensive Pos 95.0 % Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 165 NIMESULIDE Human Clinical Liver :: Clinical Chemistry :: Hepatitis increased Pos SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 165 NIMESULIDE Human Clinical Liver :: Clinical Chemistry :: Hepatocellular Damage zonal Pos SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 184 NIMESULIDE Human Clinical Blood :: PK :: T1/2 Pos 3.0 hours SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 184 NIMESULIDE Human Clinical Blood :: PK :: Cmax Pos 6.5 µg/mL SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 184 NIMESULIDE Human Clinical Blood :: PK :: Plasma Protein Binding Pos 99.0 % SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 184 NIMESULIDE Human Clinical Liver :: PK :: Clearance (CL) urinary Pos 56.0 % SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 184 NIMESULIDE Human Clinical Liver :: PK :: Clearance (CL) bile/fecal Pos 27.0 % SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 184 NIMESULIDE Human Clinical Blood :: PK :: Vd Pos 0.3 L/Kg SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 166 ACETAMINOPHEN Rat Preclinical Liver :: Clinical Chemistry :: Hepatic Necrosis increased Pos 2000.0 mg/kg/day APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 166 ACETAMINOPHEN Rat Preclinical Kidney :: Clinical Chemistry :: Nephrotoxicity Pos APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 166 ACETAMINOPHEN Rat Preclinical Liver :: mechanism :: Reactive Intermediate Pos APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 185 ACETAMINOPHEN Human Post-marketing Liver :: Clinical Chemistry :: Transaminases increased Pos 39.0 % APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 186 ACETAMINOPHEN Human Post-marketing Liver :: mechanism :: Reactive Intermediate Pos APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 186 ACETAMINOPHEN Human Post-marketing Liver :: Clinical Chemistry :: Hepatic Necrosis extensive Pos 7.5 g APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 187 ACETAMINOPHEN Human Clinical Blood :: PK :: T1/2 Pos 3.0 hours APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 187 ACETAMINOPHEN Human Clinical Blood :: PK :: Cmax Pos 21.0 µg/mL APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 187 ACETAMINOPHEN Human Clinical Blood :: PK :: Vd Pos 1.5 L/Kg APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 187 ACETAMINOPHEN Human Clinical Liver :: PK :: Sulfation Pos 30.0 APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 187 ACETAMINOPHEN Human Clinical Liver :: PK :: Clearance (CL) Kidney Pos 95.0 % APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 187 ACETAMINOPHEN Human Clinical Liver :: PK :: Clearance (CL) Pos 25.0 % APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 187 ACETAMINOPHEN Human Clinical Systemic :: PK :: Bioavailability Pos 75.0 % APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 189 NIMESULIDE Rat Preclinical Kidney :: Clinical Chemistry :: Nephrotoxicity Pos SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 189 NIMESULIDE Rat Preclinical Gut :: observation :: Gastrointestinal Toxicity Pos SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 166 ACETAMINOPHEN Rat Preclinical Systemic :: observation :: NOAEL Pos 500.0 mg/kg APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 167 CAFFEINE Rat Preclinical Systemic :: observation :: NOAEL Pos 167.0 mg/kg/day Coffeine, SID26732615, SID104171124, SID50105397, SID26752751, SID11110908, SID49718178, SID90341215, Methyltheobromine, SID50105398, Caffeine, Cafcit, SID17389997, Theine, SID124879556, NoDoz Caplets and Chewable Tablets
View 187 ACETAMINOPHEN Human Clinical Liver :: PK :: Sulfation Pos 70.0 % APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 189 NIMESULIDE Rat Preclinical Liver :: Clinical Chemistry :: Hepatoxicity Pos SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 184 NIMESULIDE Human Clinical Liver :: PK :: Metabolic Elimination extensive hydroxylation Pos SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 194 EXENATIDE Human Clinical Liver :: MRI :: MRS Pos 4.0 % AC 2993, AC-2993, AC002993, AC2993, AC2993A, Bydureon, Byetta, EXENATIDE, EXENATIDE SYNTHETIC, Exenatide Synthetic, Exenatide synthetic
View 201 Ethyl Eicosapentaenoic Acid Human Clinical Liver :: Clinical Chemistry :: ALT Change from baseline Neg 0.1592 p-value
View 197 Placebo Human Clinical None :: observation :: ALSFRS-R Change from baseline Neg -6.35 Scaled Unit
View 196 FINGOLIMOD Human Clinical None :: observation :: ALSFRS-R Drug vs Placebo Pos 0.78 p-value FINGOLIMOD, Fingolimod, GILENYA
View 196 Placebo Human Clinical None :: observation :: ALSFRS-R Total Score Pos 37.1 Scaled Unit
View 196 FINGOLIMOD Human Clinical None :: observation :: ALSFRS-R Total Score Pos 36.74 Scaled Unit FINGOLIMOD, Fingolimod, GILENYA
View 197 MCI-186 Human Clinical None :: observation :: ALSFRS-R Change from baseline Neg -5.7 Scaled Unit
View 198 IMIQUIMOD Human Clinical Vasculature :: observation :: Total Serious Adverse Events Drug vs Placebo Pos 0.0 % ALDARA, Aldara, IMIQUIMOD, R-837, S26308, ZYCLARA
View 198 IMIQUIMOD Human Clinical Vasculature :: observation :: a* (Erythemia Score) Placebo Pos 0.43 Erythemia Score ALDARA, Aldara, IMIQUIMOD, R-837, S26308, ZYCLARA
View 198 IMIQUIMOD Human Clinical Vasculature :: observation :: ΔE (Difference in Color) Pos 4.08 Erythemia Score ALDARA, Aldara, IMIQUIMOD, R-837, S26308, ZYCLARA
View 198 IMIQUIMOD Human Clinical Vasculature :: observation :: ΔE (Difference in Color) Pos 2.59 Erythemia Score ALDARA, Aldara, IMIQUIMOD, R-837, S26308, ZYCLARA
View 200 MK-4074 Human Clinical Liver :: biopsy :: Steatosis/Fatty Liver Change from baseline Neg 35.73 %
View 200 MK-4074 Human Clinical Liver :: biopsy :: Steatosis/Fatty Liver Drug vs Placebo Neg 0.001 p-value
View 200 MK-4074
PIOGLITAZONE 		Human Clinical Liver :: biopsy :: Steatosis/Fatty Liver Drug 1 vs Drug 2 Neg 0.007 p-value Actos, SID137275816, SID26756476, Pioglitazone, Duetact
View 195 EXENATIDE Human Clinical Liver :: biopsy :: Steatosis/Fatty Liver Pos 100.0 % AC 2993, AC-2993, AC002993, AC2993, AC2993A, Bydureon, Byetta, EXENATIDE, EXENATIDE SYNTHETIC, Exenatide Synthetic, Exenatide synthetic
View 201 Ethyl Eicosapentaenoic Acid Human Clinical Liver :: Clinical Chemistry :: AST Change from baseline Pos 0.0137 p-value
View 195 EXENATIDE Human Clinical Liver :: biopsy :: Steatosis/Fatty Liver Change from baseline Pos -1.5 ΔNAS AC 2993, AC-2993, AC002993, AC2993, AC2993A, Bydureon, Byetta, EXENATIDE, EXENATIDE SYNTHETIC, Exenatide Synthetic, Exenatide synthetic
View 198 IMIQUIMOD Human Clinical Vasculature :: observation :: a* (Erythemia Score) Drug Pos 1.27 Erythemia Score ALDARA, Aldara, IMIQUIMOD, R-837, S26308, ZYCLARA
View 203 Metreleptin Human Clinical Liver :: Clinical Chemistry :: NAS Score Pos 0.015 p-value
View 204 Metreleptin Human Clinical Liver :: Clinical Chemistry :: NAS Score Change from baseline Neg
View 205 EMRICASAN Human Clinical Liver :: Clinical Chemistry :: ALT Pos 0.0195 p-value EMRICASAN, IDN 6556, PF 03491390
View 206 SILYBIN A Human Clinical Liver :: Clinical Chemistry :: NAS Score Neg
View 207 LCQ908 Human Clinical Liver :: MRI :: Unspecified Change from baseline Neg 0.3128 p-value
View 208 SITAGLIPTIN PHOSPHATE Human Clinical Liver :: MRI :: PDFF Change from baseline Neg 0.585 p-value
View 209 OBETICHOLIC ACID Human Clinical Liver :: Clinical Chemistry :: NAS Score Change from baseline Pos 0.0002 p-value DSP-1747, INT-747, OBETICHOLIC ACID
View 210 Pentoxifylline Human Clinical Liver :: Clinical Chemistry :: NAS Score Change from baseline Neg -1.6 ΔNAS
View 211 Pentoxifylline Human Clinical Liver :: Clinical Chemistry :: ALT Change from baseline Neg 0.46 p-value
View 212 PIOGLITAZONE Human Clinical Liver :: Clinical Chemistry :: NAS Score Change from baseline Pos 66.666 % Actos, SID137275816, SID26756476, Pioglitazone, Duetact
View 213 PIOGLITAZONE Human Clinical Liver :: biopsy :: Steatosis/Fatty Liver Change from baseline Pos 0.001 p-value Actos, SID137275816, SID26756476, Pioglitazone, Duetact
View 201 Ethyl Eicosapentaenoic Acid Human Clinical Liver :: biopsy :: Steatosis/Fatty Liver Change from baseline Neg 0.57 p-value
View 217 Human Clinical Vasculature :: observation :: unspecified Change from baseline Pos
View 219 Human Clinical Multiple Organs :: observation :: Pain Change from baseline Pos -2.57
View 220 HYALURONIC ACID 8.0 mL Human Clinical Multiple Organs :: observation :: Pain Drug Neg 0.696 p-value Hyaluronic Acid
View 220 HYALURONIC ACID 8.0 mL Human Clinical Multiple Organs :: observation :: Pain Drug Neg 0.41 p-value Hyaluronic Acid
View 221 Human Clinical Multiple Organs :: observation :: Pain Drug Neg -124.0
View 221 Human Clinical Multiple Organs :: observation :: Pain Placebo Neg -109.0
View 221 SMC021 Oral Calcitonin 0.8 mg Human Clinical Bone :: X-ray :: Joint Space Width (JSW) Drug Neg -0.188 SMC021
View 221 SMC021 Oral Calcitonin 0.8 mg Human Clinical Bone :: X-ray :: Joint Space Width (JSW) Placebo Neg -0.198 SMC021
View 216 EVEROLIMUS 4.5 mg Human Clinical Vasculature :: observation :: unspecified Drug Pos 34.6 % AFINITOR, AFINITOR DISPERZ, CERTICAN, EVEROLIMUS, RAD001, VOTUBIA, ZORTRESS
View 216 EVEROLIMUS 4.5 mg Human Clinical Vasculature :: observation :: unspecified Placebo Neg 0.0 % AFINITOR, AFINITOR DISPERZ, CERTICAN, EVEROLIMUS, RAD001, VOTUBIA, ZORTRESS
View 216 EVEROLIMUS 4.5 mg Human Clinical Vasculature :: observation :: unspecified Drug Pos 57.7 % AFINITOR, AFINITOR DISPERZ, CERTICAN, EVEROLIMUS, RAD001, VOTUBIA, ZORTRESS
View 218 EVEROLIMUS 4.5 mg Human Clinical Brain :: observation :: Adverse Event Drug Pos 325.0 count AFINITOR, AFINITOR DISPERZ, CERTICAN, EVEROLIMUS, RAD001, VOTUBIA, ZORTRESS
View 218 EVEROLIMUS 4.5 mg Human Clinical Brain :: observation :: Adverse Event Placebo Pos 147.0 count AFINITOR, AFINITOR DISPERZ, CERTICAN, EVEROLIMUS, RAD001, VOTUBIA, ZORTRESS
View 222 ATORVASTATIN 80.0 mg Human Clinical Vasculature :: observation :: unspecified Drug Neg 0.07 p-value SID29215408, Atorvastatin, SID124892211, Lipitor, Atorvastatin hemicalcium salt
View 223 ATORVASTATIN 80.0 mg Human Clinical Multiple Organs :: Clinical Chemistry :: DNA/RNA Assay Drug Neg 0.811 p-value SID29215408, Atorvastatin, SID124892211, Lipitor, Atorvastatin hemicalcium salt
View 223 ATORVASTATIN 80.0 mg Human Clinical Multiple Organs :: Clinical Chemistry :: Protein Assay Drug Neg 0.898 p-value SID29215408, Atorvastatin, SID124892211, Lipitor, Atorvastatin hemicalcium salt
View 224 ACETAMINOPHEN Human Clinical Blood :: PK :: Cmax Pos 21.0 µg/mL APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 224 ACETAMINOPHEN Human Clinical Liver :: observation :: DILI Pos APAP, SID11112253, Acetaminophen, Infants' Feverall, SID104171293, SID17390068, Acephen, Neopap, Ofirmev, SID56422763, Tylenol, SID11114188, Datril, SID26747171, SID124882135, Injectapap, Phenaphen, Paracetamol
View 224 ACITRETIN Human Clinical Blood :: PK :: Cmax Pos 0.418 µg/mL Acitretin, SID26756475, Soriatane, SID49640651, Ro-10-1670-000, SID29216416, Etretin, Ro-101670000
View 224 ACITRETIN Human Clinical Liver :: observation :: DILI Pos Acitretin, SID26756475, Soriatane, SID49640651, Ro-10-1670-000, SID29216416, Etretin, Ro-101670000
View 224 AMIODARONE Human Clinical Blood :: PK :: Cmax Pos 0.55 µg/mL AMIODARONE, Amiodarone, CORDARONE, Cordarone, L-3428, Pacerone, SKF 33134-A, AmiodaroneHCl
View 224 AMIODARONE Human Clinical Liver :: observation :: DILI Pos AMIODARONE, Amiodarone, CORDARONE, Cordarone, L-3428, Pacerone, SKF 33134-A, AmiodaroneHCl
View 224 ASPIRIN Human Clinical Blood :: PK :: Cmax Pos 0.995 µg/mL Acetosalic Acid, Acetylsalicylic Acid, SID87798, SID17390036, Measurin, Ecotrin, SID85230910, SID26752858, 8-Hour Bayer, Salicylic Acid Acetate, SID90340586, SID47193676, SID17389202, Aspirin, Bayer Extra Strength, Equi-Prin, SID26747283, SID50105490, Acetylsalicylic acid
View 224 ASPIRIN Human Clinical Liver :: observation :: DILI Neg Acetosalic Acid, Acetylsalicylic Acid, SID87798, SID17390036, Measurin, Ecotrin, SID85230910, SID26752858, 8-Hour Bayer, Salicylic Acid Acetate, SID90340586, SID47193676, SID17389202, Aspirin, Bayer Extra Strength, Equi-Prin, SID26747283, SID50105490, Acetylsalicylic acid
View 224 ASTEMIZOLE Human Clinical Blood :: PK :: Cmax Pos 0.0005 µg/mL SID56422418, SID26751496, Astemizole, GNF-Pf-2461, R-43512, SID26751497, SID124882662, SID11112828, SID104171329, SID26746979, SID144204231, Hismanal, SID124882660, SID855746
View 224 ASTEMIZOLE Human Clinical Liver :: observation :: DILI Neg SID56422418, SID26751496, Astemizole, GNF-Pf-2461, R-43512, SID26751497, SID124882662, SID11112828, SID104171329, SID26746979, SID144204231, Hismanal, SID124882660, SID855746
View 224 ATENOLOL Human Clinical Blood :: PK :: Cmax Pos 1.33 µg/mL Esatenolol, Unibloc, SID50104387, Tenormin, ICI-66082, SID90340978, SID855957, SID26751696, Atenolol, SID50085956, Ibinolo
View 224 ATENOLOL Human Clinical Liver :: observation :: DILI Neg Esatenolol, Unibloc, SID50104387, Tenormin, ICI-66082, SID90340978, SID855957, SID26751696, Atenolol, SID50085956, Ibinolo
View 224 AZATHIOPRINE Human Clinical Blood :: PK :: Cmax Pos 1.0 µg/mL Azasan, SID90340846, Azathioprine, BW-57-322, Imuran, SID50105468, SID85230906
View 224 AZATHIOPRINE Human Clinical Liver :: observation :: DILI Pos Azasan, SID90340846, Azathioprine, BW-57-322, Imuran, SID50105468, SID85230906
View 224 AZITHROMYCIN Human Clinical Blood :: PK :: Cmax Pos 0.4 µg/mL Azasite, Azithromycin, Azithromycin Dihydrate, CP-62993, Sumamed, Sunamed, XZ-450, ZMax, Zithromax
View 224 AZITHROMYCIN Human Clinical Liver :: observation :: DILI Neg Azasite, Azithromycin, Azithromycin Dihydrate, CP-62993, Sumamed, Sunamed, XZ-450, ZMax, Zithromax
View 224 BACITRACIN Human Clinical Liver :: observation :: DILI Neg Baciferm 50, Albac 50, Bacitracin, E700, Baciim, Baci-Rx, Baciguent
View 224 BAMBUTEROL Human Clinical Blood :: PK :: Cmax Pos 0.006 µg/mL Bambuterol, SID56463628
View 224 BAMBUTEROL Human Clinical Liver :: observation :: DILI Neg Bambuterol, SID56463628
View 224 BUPIVACAINE Human Clinical Blood :: PK :: Cmax Pos 0.067 µg/mL Marcaine, SKY-0402, SID160644527, Anekain, Exparel, Bupivacaine, Sensorcaine
View 224 BUPIVACAINE Human Clinical Liver :: observation :: DILI Neg Marcaine, SKY-0402, SID160644527, Anekain, Exparel, Bupivacaine, Sensorcaine
View 224 BUSPIRONE Human Clinical Blood :: PK :: Cmax Pos 0.00192 µg/mL Buspar, SID11110857, SID11112732, SID26751994, SID11113821, Buspirone, SID90340780, SID104171117, BuspironeHCl
View 224 BUSPIRONE Human Clinical Liver :: observation :: DILI Neg Buspar, SID11110857, SID11112732, SID26751994, SID11113821, Buspirone, SID90340780, SID104171117, BuspironeHCl
View 224 CHLORPROMAZINE Human Clinical Blood :: PK :: Cmax Pos 0.3 µg/mL Largactil, SID57287810, Chlorpromazine Phenolphthalinate, SID90340916, Chlorpromazine, SID50104291, Chlorpromazine Hibenzate, Elmarin, Thorazine, Chlorpromazine Tannate, Megaphen, Sonazine, ChlorpromazineHCl
View 224 CHLORPROMAZINE Human Clinical Liver :: observation :: DILI Pos Largactil, SID57287810, Chlorpromazine Phenolphthalinate, SID90340916, Chlorpromazine, SID50104291, Chlorpromazine Hibenzate, Elmarin, Thorazine, Chlorpromazine Tannate, Megaphen, Sonazine, ChlorpromazineHCl
View 224 CISAPRIDE Human Clinical Blood :: PK :: Cmax Pos 0.06 µg/mL Propulsid, Cisapride, Risamal, R-51619, SID144204250, Acenalin
View 224 CISAPRIDE Human Clinical Liver :: observation :: DILI Neg Propulsid, Cisapride, Risamal, R-51619, SID144204250, Acenalin
View 224 CLOTRIMAZOLE Human Clinical Blood :: PK :: Cmax Pos 0.03 µg/mL Mycelex-7, Clotrimazole, Gyne-Lotrimin 3, GNF-Pf-3499, Gyne-Lotrimin Combination Pack, Mycelex, Mycelex-7 Combination Pack, SID90340692, Gynix, Trivagizole 3, Gyne-Lotrimin, BAY-5097, Canesten, Gyne-Lotrimin 3 Combination Pack, SID85230973, Mycelex-G
View 224 CLOTRIMAZOLE Human Clinical Liver :: observation :: DILI Neg Mycelex-7, Clotrimazole, Gyne-Lotrimin 3, GNF-Pf-3499, Gyne-Lotrimin Combination Pack, Mycelex, Mycelex-7 Combination Pack, SID90340692, Gynix, Trivagizole 3, Gyne-Lotrimin, BAY-5097, Canesten, Gyne-Lotrimin 3 Combination Pack, SID85230973, Mycelex-G
View 224 COLCHICINE Human Clinical Blood :: PK :: Cmax Pos 0.00564 µg/mL SID67636, SID50113686, Colchicine, SID50113685, Colcrys, SID90340644
View 224 COLCHICINE Human Clinical Liver :: observation :: DILI Neg SID67636, SID50113686, Colchicine, SID50113685, Colcrys, SID90340644
View 224 CYCLOPHOSPHAMIDE Human Clinical Blood :: PK :: Cmax Pos 69.0 µg/mL SID90341534, SID87150, Cyclophosphamide, Neosar, SID85230959, SID50105634, Sendoxan, Cytoxan
View 224 CYCLOPHOSPHAMIDE Human Clinical Liver :: observation :: DILI Pos SID90341534, SID87150, Cyclophosphamide, Neosar, SID85230959, SID50105634, Sendoxan, Cytoxan
View 224 DEFEROXAMINE MESYLATE Human Clinical Blood :: PK :: Cmax Pos 10.0 µg/mL Desferrioxamine Mesylate, Deferoxamine Mesylate, Desferal Mesylate, SID11112937, SID11533050, SID124882730, Desferal, SID26747967, Desferrioxamine Mesilate, BA-33112, Deferoxamine Mesilate, DFO
View 224 DEFEROXAMINE MESYLATE Human Clinical Liver :: observation :: DILI Pos Desferrioxamine Mesylate, Deferoxamine Mesylate, Desferal Mesylate, SID11112937, SID11533050, SID124882730, Desferal, SID26747967, Desferrioxamine Mesilate, BA-33112, Deferoxamine Mesilate, DFO
View 224 DESIPRAMINE Human Clinical Blood :: PK :: Cmax Pos 0.0168 µg/mL Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 224 DESIPRAMINE Human Clinical Liver :: observation :: DILI Neg Desipramine, Pertofrane, SID50104283, SID50100220, SID90341801, SID11111067, Norpramin, SID11111066
View 224 DEXAMETHASONE Human Clinical Blood :: PK :: Cmax Pos 0.088 µg/mL Decadron, Dexacen-4, Dexone 4, Kortico Injection, Aeroseb-Dex, Decaspray, Dexamethasone Palmitate, Maxidex, Mymethasone, Ozurdex, Dexair, Dexamethasone Intensol, Dexamethasone Metasulfobenzoate Sodium, Dexamethasone Valerate, SID26752876, Dalalone, Dexamethasone, Dexone, Dexone 0.75, Dexone 1.5, Fluormethylprednisolone, Decaderm, Decadron-LA, Dexacort, Hexadrol, SID17389945, Dexone 0.5, Neodecadron
View 224 DEXAMETHASONE Human Clinical Liver :: observation :: DILI Neg Decadron, Dexacen-4, Dexone 4, Kortico Injection, Aeroseb-Dex, Decaspray, Dexamethasone Palmitate, Maxidex, Mymethasone, Ozurdex, Dexair, Dexamethasone Intensol, Dexamethasone Metasulfobenzoate Sodium, Dexamethasone Valerate, SID26752876, Dalalone, Dexamethasone, Dexone, Dexone 0.75, Dexone 1.5, Fluormethylprednisolone, Decaderm, Decadron-LA, Dexacort, Hexadrol, SID17389945, Dexone 0.5, Neodecadron
View 224 DICLOFENAC Human Clinical Blood :: PK :: Cmax Pos 2.367 µg/mL SID24424557, Arthrotec, Diclofenac, Voltaren-XR, Cataflam, Solaraze, Voltaren, Voltaren Xr, Voltaren Ophthalmic, Cambia, DiclofenacNa
View 224 DICLOFENAC Human Clinical Liver :: observation :: DILI Pos SID24424557, Arthrotec, Diclofenac, Voltaren-XR, Cataflam, Solaraze, Voltaren, Voltaren Xr, Voltaren Ophthalmic, Cambia, DiclofenacNa
View 224 DIDANOSINE Human Clinical Blood :: PK :: Cmax Pos 0.922 µg/mL BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 224 DIDANOSINE Human Clinical Liver :: observation :: DILI Pos BMY-40900, SID29215491, SID17389541, SID26754510, SID26719672, Videx, DDI, SID26757698, Didanosine, Videx Ec, Dideoxyinosine (DDI), SID49718183
View 224 DIGOXIN Human Clinical Blood :: PK :: Cmax Pos 0.00221 µg/mL DIGOXIN, Digoxin, Digoxin pediatric, LANOXIN, Lanoxicaps, Lanoxin, Lanoxin pediatric, Vanoxin
View 224 DIGOXIN Human Clinical Liver :: observation :: DILI Neg DIGOXIN, Digoxin, Digoxin pediatric, LANOXIN, Lanoxicaps, Lanoxin, Lanoxin pediatric, Vanoxin
View 224 ERYTHROMYCIN Human Clinical Blood :: PK :: Cmax Pos 1.33 µg/mL C-Solve-2, E-Solve 2, Erythra-Derm, Ilotycin, Pce, E-Base, E-Mycin, PCE, Pfizer-E, Benzamycin, Eryc 125, Erythro 200, Staticin, Ery-Tab, Bristamycin, Emgel, Eryc Sprinkles, Erycette, Erymax, Gallimycin, A/T/S, E-Glades, ERY-TAB, Eryderm, Erythrocin, R-P Mycin, Wyamycin, Akne-Mycin, Erypar, Erythro-Statin, Erythromycin, ERYC, Erygel, Robimycin, Sansac, T-Stat
View 224 ERYTHROMYCIN Human Clinical Liver :: observation :: DILI Neg C-Solve-2, E-Solve 2, Erythra-Derm, Ilotycin, Pce, E-Base, E-Mycin, PCE, Pfizer-E, Benzamycin, Eryc 125, Erythro 200, Staticin, Ery-Tab, Bristamycin, Emgel, Eryc Sprinkles, Erycette, Erymax, Gallimycin, A/T/S, E-Glades, ERY-TAB, Eryderm, Erythrocin, R-P Mycin, Wyamycin, Akne-Mycin, Erypar, Erythro-Statin, Erythromycin, ERYC, Erygel, Robimycin, Sansac, T-Stat
View 224 ESTRADIOL Human Clinical Blood :: PK :: Cmax Pos 0.0000429 µg/mL AGOFOLLIN, ALORA, Alfatradiol, Aquagen, CLIMARA, Climara Pro, DESTRADIOL, DIHYDROTHEELIN, DIHYDROXYESTRIN, Depo-Estradiol, Divigel, E-Cypionate, ELESTRIM, ESTRACE, ESTRADERM, ESTRADIOL, ESTRADIOL HEMIHYDRATE, ESTRING, ESTROGEL, Elestrin, Esclim, Estradiol, Estradiol hemihydrate, Estrasorb, Evamist, FEMPATCH, GVNODIOL, GYNERGON, GYNOESTRYL, Gynodiol, Gynogen, INNOFEM, MENOSTAR, MINIVELLE, OESTRADIOL, Oestradiol, VAGIFEM, VIVELLE, Vagifem 18, Vagifem 8, Vivelle-Dot
View 224 ESTRADIOL Human Clinical Liver :: observation :: DILI Neg AGOFOLLIN, ALORA, Alfatradiol, Aquagen, CLIMARA, Climara Pro, DESTRADIOL, DIHYDROTHEELIN, DIHYDROXYESTRIN, Depo-Estradiol, Divigel, E-Cypionate, ELESTRIM, ESTRACE, ESTRADERM, ESTRADIOL, ESTRADIOL HEMIHYDRATE, ESTRING, ESTROGEL, Elestrin, Esclim, Estradiol, Estradiol hemihydrate, Estrasorb, Evamist, FEMPATCH, GVNODIOL, GYNERGON, GYNOESTRYL, Gynodiol, Gynogen, INNOFEM, MENOSTAR, MINIVELLE, OESTRADIOL, Oestradiol, VAGIFEM, VIVELLE, Vagifem 18, Vagifem 8, Vivelle-Dot
View 224 PYRIMETHAMINE Human Clinical Liver :: observation :: DILI Pos SID50100376, Pyrimethamine, Daraprim, Malacide, SID50104113, GNF-Pf-5586, Chloridin, TCMDC-123831, TCMDC-125860
View 224 CAPTOPRIL Human Clinical Liver :: observation :: DILI Pos CAPOTEN, CAPTOPRIL, Capoten, Captopril, Lopril, SQ 14,225, SQ-14225, Tensobon
View 224 ESTRONE Human Clinical Blood :: PK :: Cmax Pos 0.0059 µg/mL Estrogenic Substance, Estrone, Oestrone, Theelin
View 224 ESTRONE Human Clinical Liver :: observation :: DILI Pos Estrogenic Substance, Estrone, Oestrone, Theelin
View 224 FAMOTIDINE Human Clinical Blood :: PK :: Cmax Pos 0.104 µg/mL Pepcid Rpd, SID85231052, SID144203704, SID26753575, Fluxid, SID11111194, Pepcid, SID50106279, SID26748463, SID11111195, MK-208, SID49681730, SID855518, Famotidine, Pepcid Ac
View 224 FAMOTIDINE Human Clinical Liver :: observation :: DILI Neg Pepcid Rpd, SID85231052, SID144203704, SID26753575, Fluxid, SID11111194, Pepcid, SID50106279, SID26748463, SID11111195, MK-208, SID49681730, SID855518, Famotidine, Pepcid Ac
View 224 FELBAMATE Human Clinical Blood :: PK :: Cmax Pos 0.0196 µg/mL SID855835, SID11113343, SID56422162, Felbamate, Felbatol, W-554, SID50104096, SID144203696, SID90340922
View 224 FELBAMATE Human Clinical Liver :: observation :: DILI Pos SID855835, SID11113343, SID56422162, Felbamate, Felbatol, W-554, SID50104096, SID144203696, SID90340922
View 224 FENOFIBRATE Human Clinical Blood :: PK :: Cmax Pos 4.38 µg/mL Fenofibrate, Antara, Lipidil, Fenoglide, Tricor, Triglide, Lipofen
View 224 FENOFIBRATE Human Clinical Liver :: observation :: DILI Pos Fenofibrate, Antara, Lipidil, Fenoglide, Tricor, Triglide, Lipofen
View 224 FLUOXETINE Human Clinical Blood :: PK :: Cmax Pos 0.015 µg/mL Prozac, Sarafem, Symbyax, SID104171153, SID26755310, SID26751973, SID50104648, Fluoxetine, SID90341619, SID144203695, Prozac Weekly, FluoxetineHCl
View 224 FLUOXETINE Human Clinical Liver :: observation :: DILI Neg Prozac, Sarafem, Symbyax, SID104171153, SID26755310, SID26751973, SID50104648, Fluoxetine, SID90341619, SID144203695, Prozac Weekly, FluoxetineHCl
View 224 FLUTAMIDE Human Clinical Blood :: PK :: Cmax Pos 0.1 µg/mL SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 224 FLUTAMIDE Human Clinical Liver :: observation :: DILI Pos SID26753015, SID104171162, SID17388997, SID26747366, SID144203705, Flutamide, SCH-13521, SID85231055, SID11532925, SID90341271, Drogenil, SID50105597, SID124880151, SID50105599, SID26747365, SID50105598, SID49675006, Eulexin, SID26753014, SID11111203, SID11111202, SID124880153, SID50105600
View 224 FLUVASTATIN Human Clinical Blood :: PK :: Cmax Pos 0.273 µg/mL Fluvastatin
View 224 FLUVASTATIN Human Clinical Liver :: observation :: DILI Neg Fluvastatin
View 224 FUROSEMIDE Human Clinical Blood :: PK :: Cmax Pos 1.08 µg/mL Aquamed, Disal, FRUSEMIDE, FUROSEMIDE, Frusemide, Furosemide, LASIX, LB-502
View 224 FUROSEMIDE Human Clinical Liver :: observation :: DILI Pos Aquamed, Disal, FRUSEMIDE, FUROSEMIDE, Frusemide, Furosemide, LASIX, LB-502
View 224 GABAPENTIN Human Clinical Blood :: PK :: Cmax Pos 2.474 µg/mL SID90340599, SID50103936, SID11112806, SID11113327, SID104171164, Gabapentin, Neurontin, SID855579, CI-945, GOE-3450, Gralise
View 224 GABAPENTIN Human Clinical Liver :: observation :: DILI Neg SID90340599, SID50103936, SID11112806, SID11113327, SID104171164, Gabapentin, Neurontin, SID855579, CI-945, GOE-3450, Gralise
View 224 GLAFENINE Human Clinical Blood :: PK :: Cmax Pos 0.7 µg/mL Glycerylaminophenaquine, Glaphenine, R-1707, Glafenine, SID26748455
View 224 GLAFENINE Human Clinical Liver :: observation :: DILI Pos Glycerylaminophenaquine, Glaphenine, R-1707, Glafenine, SID26748455
View 224 GLIMEPIRIDE Human Clinical Blood :: PK :: Cmax Pos 0.551 µg/mL SID49648856, HOE-490, Glimepiride, Amaryl
View 224 GLIMEPIRIDE Human Clinical Liver :: observation :: DILI Neg SID49648856, HOE-490, Glimepiride, Amaryl
View 224 INDOMETHACIN Human Clinical Blood :: PK :: Cmax Pos 2.0 µg/mL SID90340917, Indocin, Indometacin, Indomethacin, Desmethyl indomethacin, SID856012, Indocin SR, Indo-Lemmon, Indometacin Farnesil, SID85231093, SID56422212
View 224 INDOMETHACIN Human Clinical Liver :: observation :: DILI Pos SID90340917, Indocin, Indometacin, Indomethacin, Desmethyl indomethacin, SID856012, Indocin SR, Indo-Lemmon, Indometacin Farnesil, SID85231093, SID56422212
View 224 ISONIAZID Human Clinical Blood :: PK :: Cmax Pos 10.5 µg/mL SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 224 ISONIAZID Human Clinical Liver :: observation :: DILI Pos SID26746988, SID121269825, Dow-Isoniazid, Nydrazid, SID49718175, Isonicotinylhydrazine, Laniazid, Rimifon, SID11112128, SID26751504, Hyzyd, Isoniazid, SID17389848, SID124881933, Stanozide, INH, SID855769, Isoniazide
View 224 ISOTRETINOIN Human Clinical Blood :: PK :: Cmax Pos 0.301 µg/mL Ro-43780, Absorica, Isotretinoin, SID90341473, Accutane, Myorisan, SID47193696, SID50106981, Sotret, 13 Cis-Retinoic Acid, Claravis, Amnesteem
View 224 ISOTRETINOIN Human Clinical Liver :: observation :: DILI Pos Ro-43780, Absorica, Isotretinoin, SID90341473, Accutane, Myorisan, SID47193696, SID50106981, Sotret, 13 Cis-Retinoic Acid, Claravis, Amnesteem
View 224 L-ARGININE Human Clinical Liver :: observation :: DILI Neg SID50104526, Arginine, SID11113629, SID90341198, R-Gene, SID11110746
View 224 LEVODOPA Human Clinical Blood :: PK :: Cmax Pos 1.35 µg/mL levodopa, L-dopa, Dopar, 3,4-dihydroxy-L-phenylalanine, 59-92-7, 3-Hydroxy-L-tyrosine, Bendopa, Dopasol, Larodopa, Levopa, Cidandopa, Dopaidan, Dopalina, Insulamina, Maipedopa, Eldopal, Eldopar, Pardopa, Prodopa, Syndopa, Helfo-Dopa, Dopaflex, Dopaston, Doparl, (-)-Dopa, Dihydroxy-L-phenylalanine, 3-(3,4-Dihydroxyphenyl)-L-alanine, 3,4-Dihydroxyphenylalanine, Brocadopa, Doparkine, Dopastral, Eldopatec, Eurodopa, Levedopa, Deadopa, Doprin, Veldopa, Dopal-fher, Ledopa, Dopal, Weldopa, Parda, L-o-Hydroxytyrosine, Dopa, 3,4-Dihydroxyphenyl-L-alanine, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid, L-Dihydroxyphenylalanine, Laradopa, Levodopum, (-)-3-(3,4-Dihydroxyphenyl)-L-alanine, L-3-Hydroxytyrosine, L-Tyrosine 3-hydroxy-, L-(-)-Dopa, Dopaston SE, L-(o-Dihydroxyphenyl)alanine, L-3,4-Dihydroxyphenylalanine, L-beta-(3,4-Dihydroxyphenyl)alanine, Biodopa, Cerepap, Sobiodopa, beta-(3,4-Dihydroxyphenyl)-L-alanine, beta-(3,4-Dihydroxyphenyl)alanine, L-3-(3,4-Dihydroxyphenyl)alanine, Helfo DOPA, L Dopa, Ro 4-6316, component of Sinemet, Dopar (TN), Tyrosine 3-hydroxy-, Dopastone, Dopicar, Levodopum [INN-Latin], CHEBI:15765, L(-)-Dopa, IV Levodopa, L-O-Dihydroxyphenylalanine, alanine 3-(3,4-dihydroxyphenyl)-, L-, (-)-(3,4-Dihydroxyphenyl)alanine, beta-(3,4-Dihydroxyphenyl)-alpha-L-alanine, L-beta-(3,4-Dihydroxyphenyl)-alpha-alanine, CHEMBL1009, Prestwick_185, CCRIS 3766, L-.beta.-(3,4-Dihydroxyphenyl)alanine, .beta.-(3,4-Dihydroxyphenyl)-L-alanine, S1726_Selleck, HSDB 3348, Spectrum_000454, UNII-46627O600J, 3,4-Dihydroxyphenylalanine (VAN), Alanine 3-(3,4-dihydroxyphenyl)-, (-)-, AC1L1LOR, Prestwick0_000017, Prestwick1_000017, Prestwick2_000017, Prestwick3_000017, Spectrum2_000496, Spectrum4_000539, Spectrum5_001899, EINECS 200-445-2, Lopac-D-9628, dihydroxyphenylalanine, Levodopa (JP15/USP), NSC118381, bmse000322, NSC 118381, AC1Q4U7F, (S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid, CAS-59-92-7, 3 4-Dihydroxyphenylalanine, Lopac0_000454, BSPBio_000053, BSPBio_002354, KBioGR_001177, KBioSS_000934, L-4-5-Dihydroxyphenylalanine, beta-(3,4-Dihydroxyphenyl)-alpha-alanine, BIDD:GT0158, Bio-0575, D9628_SIGMA, DivK1c_000452, SPBio_000391, SPBio_001974, SPECTRUM2300205, MLS000028514, BPBio1_000059, b-(3,4-Dihydroxyphenyl)alanine, 3 4-Dihydroxy-L-phenylalanine, 37830_FLUKA, HMS501G14, KBio1_000452, KBio2_000934, KBio2_003502, KBio2_006070, L-(3,4-Dihydroxyphenyl)alanine, Levodopa [USAN:INN:BAN:JAN], NINDS_000452, L-(3 4-Dihydroxyphenyl)alanine, WTDRDQBEARUVNC-LURJTMIESA-N, HMS1568C15, HMS1922J14, HMS2090O08, HMS2093N04, b-(3,4-Dihydroxyphenyl)-L-alanine, L-3-(3,4-dihydroxyphenyl)-Alanine, Alanine 3-(3,4-dihydroxyphenyl)-, LS-255, MFCD00002598, PDSP1_001541, PDSP2_001525, .beta.-(3,4-Dihydroxyphenyl)alanine, C9H11NO4, b-(3,4-Dihydroxyphenyl)-a-L-alanine, L-b-(3,4-Dihydroxyphenyl)-a-alanine, .beta.-(3 4-Dihydroxyphenyl)alanine, DB01235, SDCCGMLS-0066924.P001, IDI1_000452, NCGC00015384-01, NCGC00016270-01, NCGC00016270-04, NCGC00016270-06, NCGC00093869-04, SMR000058312, L-(3,4-Dihydroxyphenyl)-.alpha.-alanine, D0600, D9628, EU-0100454, Alanine 3-(3, 4-dihydroxyphenyl)-, (-)-, C00355, D 9628, D00059, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate, 587-45-1, DAH, 1E83F927-C221-46AA-B90A-81B33C5F3868, 23734-74-9, 25525-15-9, 34241-25-3, 72572-99-7, 72573-00-3, 88250-23-1, 90638-38-3, L-DOPA Parcopa, Atamet, Stalevo, Madopar, Prolopa, Dopar, 3,4-Dihydroxyphenylalanine, Levodopa, L-3,4-Dihydrophenylalanine, WLN: QVYZ1R CQ DQ, Sinemetreg, Bidopal, CID6047, l)-L-alanine, L-DOPA; Levodopa, Madopa (Salt/Mix), nchembio.89-comp9, 3-(3,4-Dihydroxypheny, DSSTox_CID_3209, Epitope ID:150927, Alanine,4-dihydroxyphenyl)-, DSSTox_RID_76926, DSSTox_GSID_23209, SCHEMBL22655, L-Dopa L-3-Hydroxytyrosine, Levodopa (JP15/USP/INN), Levodopa (JP17/USP/INN), nchembio.2007.55-comp26, GTPL3639, (S)-3,4-dihydroxyphenylalanine, DTXSID9023209, WLN: QVYZ1R CQ DQ -L, CTK1H2187, HMDB00181, Alanine,4-dihydroxyphenyl)- L-, HMS2095C15, HMS2230B04, HMS3261K10, Pharmakon1600-0230020
View 224 LEVODOPA Human Clinical Liver :: observation :: DILI Neg levodopa, L-dopa, Dopar, 3,4-dihydroxy-L-phenylalanine, 59-92-7, 3-Hydroxy-L-tyrosine, Bendopa, Dopasol, Larodopa, Levopa, Cidandopa, Dopaidan, Dopalina, Insulamina, Maipedopa, Eldopal, Eldopar, Pardopa, Prodopa, Syndopa, Helfo-Dopa, Dopaflex, Dopaston, Doparl, (-)-Dopa, Dihydroxy-L-phenylalanine, 3-(3,4-Dihydroxyphenyl)-L-alanine, 3,4-Dihydroxyphenylalanine, Brocadopa, Doparkine, Dopastral, Eldopatec, Eurodopa, Levedopa, Deadopa, Doprin, Veldopa, Dopal-fher, Ledopa, Dopal, Weldopa, Parda, L-o-Hydroxytyrosine, Dopa, 3,4-Dihydroxyphenyl-L-alanine, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid, L-Dihydroxyphenylalanine, Laradopa, Levodopum, (-)-3-(3,4-Dihydroxyphenyl)-L-alanine, L-3-Hydroxytyrosine, L-Tyrosine 3-hydroxy-, L-(-)-Dopa, Dopaston SE, L-(o-Dihydroxyphenyl)alanine, L-3,4-Dihydroxyphenylalanine, L-beta-(3,4-Dihydroxyphenyl)alanine, Biodopa, Cerepap, Sobiodopa, beta-(3,4-Dihydroxyphenyl)-L-alanine, beta-(3,4-Dihydroxyphenyl)alanine, L-3-(3,4-Dihydroxyphenyl)alanine, Helfo DOPA, L Dopa, Ro 4-6316, component of Sinemet, Dopar (TN), Tyrosine 3-hydroxy-, Dopastone, Dopicar, Levodopum [INN-Latin], CHEBI:15765, L(-)-Dopa, IV Levodopa, L-O-Dihydroxyphenylalanine, alanine 3-(3,4-dihydroxyphenyl)-, L-, (-)-(3,4-Dihydroxyphenyl)alanine, beta-(3,4-Dihydroxyphenyl)-alpha-L-alanine, L-beta-(3,4-Dihydroxyphenyl)-alpha-alanine, CHEMBL1009, Prestwick_185, CCRIS 3766, L-.beta.-(3,4-Dihydroxyphenyl)alanine, .beta.-(3,4-Dihydroxyphenyl)-L-alanine, S1726_Selleck, HSDB 3348, Spectrum_000454, UNII-46627O600J, 3,4-Dihydroxyphenylalanine (VAN), Alanine 3-(3,4-dihydroxyphenyl)-, (-)-, AC1L1LOR, Prestwick0_000017, Prestwick1_000017, Prestwick2_000017, Prestwick3_000017, Spectrum2_000496, Spectrum4_000539, Spectrum5_001899, EINECS 200-445-2, Lopac-D-9628, dihydroxyphenylalanine, Levodopa (JP15/USP), NSC118381, bmse000322, NSC 118381, AC1Q4U7F, (S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid, CAS-59-92-7, 3 4-Dihydroxyphenylalanine, Lopac0_000454, BSPBio_000053, BSPBio_002354, KBioGR_001177, KBioSS_000934, L-4-5-Dihydroxyphenylalanine, beta-(3,4-Dihydroxyphenyl)-alpha-alanine, BIDD:GT0158, Bio-0575, D9628_SIGMA, DivK1c_000452, SPBio_000391, SPBio_001974, SPECTRUM2300205, MLS000028514, BPBio1_000059, b-(3,4-Dihydroxyphenyl)alanine, 3 4-Dihydroxy-L-phenylalanine, 37830_FLUKA, HMS501G14, KBio1_000452, KBio2_000934, KBio2_003502, KBio2_006070, L-(3,4-Dihydroxyphenyl)alanine, Levodopa [USAN:INN:BAN:JAN], NINDS_000452, L-(3 4-Dihydroxyphenyl)alanine, WTDRDQBEARUVNC-LURJTMIESA-N, HMS1568C15, HMS1922J14, HMS2090O08, HMS2093N04, b-(3,4-Dihydroxyphenyl)-L-alanine, L-3-(3,4-dihydroxyphenyl)-Alanine, Alanine 3-(3,4-dihydroxyphenyl)-, LS-255, MFCD00002598, PDSP1_001541, PDSP2_001525, .beta.-(3,4-Dihydroxyphenyl)alanine, C9H11NO4, b-(3,4-Dihydroxyphenyl)-a-L-alanine, L-b-(3,4-Dihydroxyphenyl)-a-alanine, .beta.-(3 4-Dihydroxyphenyl)alanine, DB01235, SDCCGMLS-0066924.P001, IDI1_000452, NCGC00015384-01, NCGC00016270-01, NCGC00016270-04, NCGC00016270-06, NCGC00093869-04, SMR000058312, L-(3,4-Dihydroxyphenyl)-.alpha.-alanine, D0600, D9628, EU-0100454, Alanine 3-(3, 4-dihydroxyphenyl)-, (-)-, C00355, D 9628, D00059, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate, 587-45-1, DAH, 1E83F927-C221-46AA-B90A-81B33C5F3868, 23734-74-9, 25525-15-9, 34241-25-3, 72572-99-7, 72573-00-3, 88250-23-1, 90638-38-3, L-DOPA Parcopa, Atamet, Stalevo, Madopar, Prolopa, Dopar, 3,4-Dihydroxyphenylalanine, Levodopa, L-3,4-Dihydrophenylalanine, WLN: QVYZ1R CQ DQ, Sinemetreg, Bidopal, CID6047, l)-L-alanine, L-DOPA; Levodopa, Madopa (Salt/Mix), nchembio.89-comp9, 3-(3,4-Dihydroxypheny, DSSTox_CID_3209, Epitope ID:150927, Alanine,4-dihydroxyphenyl)-, DSSTox_RID_76926, DSSTox_GSID_23209, SCHEMBL22655, L-Dopa L-3-Hydroxytyrosine, Levodopa (JP15/USP/INN), Levodopa (JP17/USP/INN), nchembio.2007.55-comp26, GTPL3639, (S)-3,4-dihydroxyphenylalanine, DTXSID9023209, WLN: QVYZ1R CQ DQ -L, CTK1H2187, HMDB00181, Alanine,4-dihydroxyphenyl)- L-, HMS2095C15, HMS2230B04, HMS3261K10, Pharmakon1600-0230020
View 224 LEVOFLOXACIN Human Clinical Blood :: PK :: Cmax Pos 5.7 µg/mL Levofloxacin, Iquix, RWJ-25213, DR-3355, Levaquin, Quixin, SID49665952, Floxacin, SID26719895
View 224 LEVOFLOXACIN Human Clinical Liver :: observation :: DILI Neg Levofloxacin, Iquix, RWJ-25213, DR-3355, Levaquin, Quixin, SID49665952, Floxacin, SID26719895
View 224 LIDOCAINE Human Clinical Blood :: PK :: Cmax Pos 8.5 µg/mL Xylocaine, Lignocaine Hcl, Anestacon, SID56422194, Iontocaine, Octocaine, SID26751484, Alphacaine, Lidopen, SID104171182, SID11111385, SID855682, Lignocaine, SID26751483, Dentipatch, Embolex, Lidocaton, Lidoderm, Lidocaine, Terramycin, Lignostab, LMX, SID90340642, SID11111384
View 224 LIDOCAINE Human Clinical Liver :: observation :: DILI Neg Xylocaine, Lignocaine Hcl, Anestacon, SID56422194, Iontocaine, Octocaine, SID26751484, Alphacaine, Lidopen, SID104171182, SID11111385, SID855682, Lignocaine, SID26751483, Dentipatch, Embolex, Lidocaton, Lidoderm, Lidocaine, Terramycin, Lignostab, LMX, SID90340642, SID11111384
View 224 LISINOPRIL Human Clinical Blood :: PK :: Cmax Pos 0.29 µg/mL LISINOPRIL, MK-521, Lisinopril Dihydrate
View 224 LISINOPRIL Human Clinical Liver :: observation :: DILI Pos LISINOPRIL, MK-521, Lisinopril Dihydrate
View 224 LOVASTATIN Human Clinical Blood :: PK :: Cmax Pos 0.01 µg/mL SID17389841, SID26751557, Altoprev, SID49732779, SID855905, Lovastatin, SID496591, MK-803, Mevacor, Mevinolin, SID144204439
View 224 LOVASTATIN Human Clinical Liver :: observation :: DILI Neg SID17389841, SID26751557, Altoprev, SID49732779, SID855905, Lovastatin, SID496591, MK-803, Mevacor, Mevinolin, SID144204439
View 224 MALEIC ACID Human Clinical Liver :: observation :: DILI Pos maleic acid, cis-butenedioic acid, Toxilic acid, 110-16-7, Maleinic acid, Malenic acid, maleate, (Z)-Butenedioic acid, 2-Butenedioic acid (Z)-, Kyselina maleinova, (2Z)-but-2-enedioic acid, cis-1,2-Ethylenedicarboxylic acid, (Z)-2-Butenedioic acid, 2-Butenedioic acid (2Z)-, 2-Butenedioic acid, cis-2-Butenedioic acid, Malezid CM, Butenedioic acid, (Z)-, 2-Butenedioic acid, (Z)-, Cis-butenedioate, 2-Butenedioate, (z)-butenedioate, H2male, 1,2-Ethylenedicarboxylic acid, (Z), cis-2-Butenedioate, cis-but-2-enedioate, Scotchbond Multipurpose Etchant, Sodium maleate, CCRIS 1115, HSDB 666, (2Z)-2-Butenedioate, cis-but-2-enedioic acid, (2Z)-but-2-enedioate, (2Z)-Butene-2-dioate, But-2-enedioic acid, (2Z)-2-Butenedioic acid, Kyselina maleinova [Czech], Maleic acid [NA2215], (Z)-2-Butenedioate, (2Z)-Butene-2-dioic acid, UNII-91XW058U2C, AI3-01002, CHEBI:18300, VZCYOOQTPOCHFL-UPHRSURJSA-N, EINECS 203-742-5, Maleic acid [NA2215] [Corrosive], MFCD00063177, NA2215, NSC 25940, SBB040567, MAE, BRN 0605762, DSSTox_CID_1517, (2Z)but-2-enedioic acid, (Z)-but-2-enedioic acid, DSSTox_RID_76194, DSSTox_GSID_21517, CAS-110-16-7, C4H4O4, Acidum maleicum, 1ahy, 1tok, L-Maleic Acid, NCGC00091192-02, bis-hydrogen maleate, MALEICACID, Maleic acid (8CI), PubChem21784, Butenedioic acid,(Z)-, SCHEMBL613, bmse000212, WLN: QV1U1VQ-C, AC1L9G1A, MLS002153468, 2-butenedioic acid, (2Z)-, (2Z)-2-Butenedioic acid #, AC1Q71E5, CHEMBL539648, M0375_SIAL, DTXSID8021517, 63189_FLUKA, HMDB00176, InChI=1/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1, 91XW058U2C, HMS2236F09, cis-Butenedioic acid; Toxilic acid, 2-Butenedioic acid (Z)- (9CI), 6915-18-0, NSC25940, STR03481, 10237-70-4 (potassium salt), Tox21_113105, Tox21_202193, Tox21_303045, 1,2-Ethylenedicarboxylic acid, cis-, 2-Butenedioic acid (2Z)- (9CI), 37449-49-3 (Nd salt), LS-499, NSC-25940, ZINC12358683, 371-47-1 (di-hydrochloride salt), 18016-19-8 (hydrochloride salt), AKOS000268822, Tox21_113105_1, 44742-89-4 (mono-ammonium salt), Maleic acid [NA2215] [Corrosive], RP19212, 3105-55-3 (mono-hydrochloride salt), Maleic anhydride, mono(castor oil) ester, NCGC00090970-01, NCGC00090970-02, NCGC00090970-03, NCGC00257215-01, NCGC00259742-01, 4CN-0931, AK109350, AN-22588, BT000111, KB-53311, OR036502, OR180703, OR194615, OR271441, SMR001230824, AB1009478, 102-EP2269610A2, 102-EP2269983A1, 102-EP2269984A1, 102-EP2269988A2, 102-EP2269989A1, 102-EP2269990A1, 102-EP2270002A1, 102-EP2270003A1, 102-EP2270006A1, 102-EP2270008A1, 102-EP2270011A1, 102-EP2270505A1, 102-EP2272537A2, 102-EP2272822A1, 102-EP2272827A1, 102-EP2272834A1, 102-EP2272849A1, 102-EP2275401A1, 102-EP2275411A2, 102-EP2275412A1, 102-EP2275413A1, 102-EP2275414A1, 102-EP2277507A1, 102-EP2277848A1, 102-EP2277858A1, 102-EP2277866A1, 102-EP2277867A2, 102-EP2280003A2, 102-EP2280006A1, 102-EP2280009A1, 102-EP2280010A2, 102-EP2280012A2, 102-EP2281559A1, 102-EP2281563A1, 102-EP2281819A1, 102-EP2281823A2, 102-EP2284149A1, 102-EP2284160A1, 102-EP2284169A1, 102-EP2284178A2, 102-EP2284179A2, 102-EP2286795A1, 102-EP2287147A2, 102-EP2287153A1, 102-EP2287155A1, 102-EP2287156A1, 102-EP2287160A1, 102-EP2287161A1, 102-EP2287162A1, 102-EP2289510A1, 102-EP2289518A1, 102-EP2289879A1, 102-EP2289883A1, 102-EP2289890A1, 102-EP2289894A2, 102-EP2292227A2, 102-EP2292228A1, 102-EP2292231A1, 102-EP2292234A1, 102-EP2292592A1, 102-EP2292611A1, 102-EP2292615A1, 102-EP2292617A1, 102-EP2292619A1, 102-EP2295401A2, 102-EP2295402A2, 102-EP2295406A1, 102-EP2295415A1, 102-EP2295416A2, 102-EP2295418A1, 102-EP2295424A1, 102-EP2295426A1, 102-EP2295427A1, 102-EP2295433A2, 102-EP2295437A1, 102-EP2298731A1, 102-EP2298734A2, 102-EP2298735A1, 102-EP2298746A1, 102-EP2298747A1, 102-EP2298748A2, 102-EP2298755A1, 102-EP2298757A2, 102-EP2298758A1, 102-EP2298759A1, 102-EP2298767A1, 102-EP2298772A1, 102-EP2298775A1, 102-EP2298779A1, 102-EP2301544A1, 102-EP2301922A1, 102-EP2301923A1, 102-EP2301924A1, 102-EP2301928A1, 102-EP2301929A1, 102-EP2301931A1, 102-EP2301933A1, 102-EP2301935A1, 102-EP2301937A1, 102-EP230194
View 224 METHOTREXATE Human Clinical Blood :: PK :: Cmax Pos 0.351 µg/mL TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 224 METHOTREXATE Human Clinical Liver :: observation :: DILI Pos TCMDC-125858, TCMDC-125488, SID50104778, SID124886991, Trexall, CL-14377, SID90340825, SID11113978, Mexate, SID26752122, SID144204495, Methylaminopterin, SID50104777, SID56463665, SID26752121, Amethopterin, TCMDC-123832, SID67627, SID26752120, Methotrexate, Abitrexate, Folex, Mexate-AQ, Rheumatrex
View 224 MICONAZOLE Human Clinical Blood :: PK :: Cmax Pos 0.01 µg/mL Monistat-3, SID443253, Vusion, Micatin, Monistat, Conofite, Oravig, Monistat-Derm, SID144204152, SID85148356, Miconazole, Dermazole
View 224 MICONAZOLE Human Clinical Liver :: observation :: DILI Neg Monistat-3, SID443253, Vusion, Micatin, Monistat, Conofite, Oravig, Monistat-Derm, SID144204152, SID85148356, Miconazole, Dermazole
View 224 MONTELUKAST Human Clinical Blood :: PK :: Cmax Pos 0.38 µg/mL MK-476, Singulair, Montelukast, Montelo-10
View 224 MONTELUKAST Human Clinical Liver :: observation :: DILI Neg MK-476, Singulair, Montelukast, Montelo-10
View 224 NADOLOL Human Clinical Blood :: PK :: Cmax Pos 0.13 µg/mL Nadolol, SQ-11725, SID855594, SID56422422, Corgard
View 224 NADOLOL Human Clinical Liver :: observation :: DILI Neg Nadolol, SQ-11725, SID855594, SID56422422, Corgard
View 224 NALTREXONE Human Clinical Blood :: PK :: Cmax Pos 0.02 µg/mL Celupan, EN-1639A, Revia, Naltrexone, EN-1639A [As Hydrochloride], Vivitrol, Trexal, Trexan
View 224 NALTREXONE Human Clinical Liver :: observation :: DILI Pos Celupan, EN-1639A, Revia, Naltrexone, EN-1639A [As Hydrochloride], Vivitrol, Trexal, Trexan
View 224 NEFAZODONE Human Clinical Blood :: PK :: Cmax Pos 0.4349 µg/mL Nefazodone, Serzone, SID50111710, SID49666410, Nefadar, Nefazodone Hydrochloride
View 224 NEFAZODONE Human Clinical Liver :: observation :: DILI Pos Nefazodone, Serzone, SID50111710, SID49666410, Nefadar, Nefazodone Hydrochloride
View 224 NIACIN Human Clinical Blood :: PK :: Cmax Pos 18.0 µg/mL NIACIN, NIACOR, NIASPAN, NIASPAN TITRATION STARTER PACK, NICANGIN, NICOLAR, NICOTINIC ACID, Niacin, Niacin TD, Niaspan ER, Nicotinate, Simcor, WAMPOCAP
View 224 NIACIN Human Clinical Liver :: observation :: DILI Pos NIACIN, NIACOR, NIASPAN, NIASPAN TITRATION STARTER PACK, NICANGIN, NICOLAR, NICOTINIC ACID, Niacin, Niacin TD, Niaspan ER, Nicotinate, Simcor, WAMPOCAP
View 224 NIMESULIDE Human Clinical Blood :: PK :: Cmax Pos 6.5 µg/mL SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 224 NIMESULIDE Human Clinical Liver :: observation :: DILI Pos SID85231150, SID56422364, SID26746940, SID50103974, Nimesulide, SID11111521, SID26751468, R-805, SID11111520, SID124880853, SID855635
View 224 NOMIFENSINE Human Clinical Blood :: PK :: Cmax Pos 0.136 µg/mL Alival, SID50105261, Merital, Nomifensine, SID90340560
View 224 NOMIFENSINE Human Clinical Liver :: observation :: DILI Pos Alival, SID50105261, Merital, Nomifensine, SID90340560
View 224 OXYPHENONIUM Human Clinical Liver :: observation :: DILI Neg Oxyphenonium
View 224 PAROXETINE Human Clinical Blood :: PK :: Cmax Pos 0.02 µg/mL BRL-29060, Paroxetine, Paxil, SID50104981, SID26752262, SID144206674, SID50104978, SID50104979, SID50104980, SID29215051, SID90341371, Paxil [as hydrochloride], Pexeva
View 224 PAROXETINE Human Clinical Liver :: observation :: DILI Neg BRL-29060, Paroxetine, Paxil, SID50104981, SID26752262, SID144206674, SID50104978, SID50104979, SID50104980, SID29215051, SID90341371, Paxil [as hydrochloride], Pexeva
View 224 PERHEXILINE Human Clinical Blood :: PK :: Cmax Pos 0.6 µg/mL Perhexiline
View 224 PERHEXILINE Human Clinical Liver :: observation :: DILI Pos Perhexiline
View 224 PHENACETIN Human Clinical Blood :: PK :: Cmax Pos 2.4 µg/mL Phenacetin, SID11112166, Acetphenetidin, Acetophenetidin, SID144203898, SID124882016
View 224 PHENACETIN Human Clinical Liver :: observation :: DILI Pos Phenacetin, SID11112166, Acetphenetidin, Acetophenetidin, SID144203898, SID124882016
View 224 PHENYLBUTAZONE Human Clinical Blood :: PK :: Cmax Pos 150.0 µg/mL Elmedal, SID144203794, Pro-Bute, Azolid, SID17389760, Diphenylbutazone, Equiphar, SID50104199, SID85231197, Butaject, SID56436656, SID104171221, Butazolidin, Phenylbutazone, Antadol, SID855958, SID11111674, SID26751573, SID26747057, SID104171220, SID90341773
View 224 PHENYLBUTAZONE Human Clinical Liver :: observation :: DILI Pos Elmedal, SID144203794, Pro-Bute, Azolid, SID17389760, Diphenylbutazone, Equiphar, SID50104199, SID85231197, Butaject, SID56436656, SID104171221, Butazolidin, Phenylbutazone, Antadol, SID855958, SID11111674, SID26751573, SID26747057, SID104171220, SID90341773
View 224 PILOCARPINE Human Clinical Blood :: PK :: Cmax Pos 0.0205 µg/mL Ocusert Pilo, Pilocarpine
View 224 PILOCARPINE Human Clinical Liver :: observation :: DILI Neg Ocusert Pilo, Pilocarpine
View 224 PIOGLITAZONE Human Clinical Blood :: PK :: Cmax Pos 1.05 µg/mL Actos, SID137275816, SID26756476, Pioglitazone, Duetact
View 224 PIOGLITAZONE Human Clinical Liver :: observation :: DILI Neg Actos, SID137275816, SID26756476, Pioglitazone, Duetact
View 224 PROGESTERONE Human Clinical Blood :: PK :: Cmax Pos 0.0606 µg/mL CRINONE, Crinone, ENDOMETRIN, Endometrin, Gesterol, PROGESTERONE, PROMETRIUM, Progestasert, Progesterone, Progestin, Prometrium, Regumate, Syngestrone
View 224 PROGESTERONE Human Clinical Liver :: observation :: DILI Pos CRINONE, Crinone, ENDOMETRIN, Endometrin, Gesterol, PROGESTERONE, PROMETRIUM, Progestasert, Progesterone, Progestin, Prometrium, Regumate, Syngestrone
View 224 PROPRANOLOL Human Clinical Blood :: PK :: Cmax Pos 0.052 µg/mL Propranolol, SID26751802, Inderide-40/25, SID124881056, Innopran Xl, Inderal, SID50104497, Inderide-80/25, SID90341556, SID26755283
View 224 PROPRANOLOL Human Clinical Liver :: observation :: DILI Neg Propranolol, SID26751802, Inderide-40/25, SID124881056, Innopran Xl, Inderal, SID50104497, Inderide-80/25, SID90341556, SID26755283
View 224 PYRIMETHAMINE Human Clinical Blood :: PK :: Cmax Pos 0.818 µg/mL SID50100376, Pyrimethamine, Daraprim, Malacide, SID50104113, GNF-Pf-5586, Chloridin, TCMDC-123831, TCMDC-125860
View 224 RALOXIFENE Human Clinical Blood :: PK :: Cmax Pos 0.0005 µg/mL Evista, RALOXIFENE, Raloxifene
View 224 RALOXIFENE Human Clinical Liver :: observation :: DILI Neg Evista, RALOXIFENE, Raloxifene
View 224 ROSIGLITAZONE Human Clinical Blood :: PK :: Cmax Pos 0.373 µg/mL Avandaryl, Avandia, Rosiglitazone, SID26748954, SID144204987, Avandamet, BRL-49653
View 224 ROSIGLITAZONE Human Clinical Liver :: observation :: DILI Neg Avandaryl, Avandia, Rosiglitazone, SID26748954, SID144204987, Avandamet, BRL-49653
View 224 SERTRALINE Human Clinical Blood :: PK :: Cmax Pos 0.0245 µg/mL SID50105685, SID50105684, Zoloft, SID50105682, SID49665783, SID90341218, SID29215139, Sertraline, SID26753299, SID50105683
View 224 SERTRALINE Human Clinical Liver :: observation :: DILI Neg SID50105685, SID50105684, Zoloft, SID50105682, SID49665783, SID90341218, SID29215139, Sertraline, SID26753299, SID50105683
View 224 SIMVASTATIN Human Clinical Blood :: PK :: Cmax Pos 0.01 µg/mL MK-733, Synvinolin, Simvastatin, Simvastatin hydroxy acid, SID496592, Zocor, SID50086525, SID144204247
View 224 SIMVASTATIN Human Clinical Liver :: observation :: DILI Neg MK-733, Synvinolin, Simvastatin, Simvastatin hydroxy acid, SID496592, Zocor, SID50086525, SID144204247
View 224 STAVUDINE Human Clinical Blood :: PK :: Cmax Pos 0.7764 µg/mL d4T, D4T, SID855856, Zerit Xr, BMY-27857, Stavudine, SID7971664, SID90341632, Zerit
View 224 STAVUDINE Human Clinical Liver :: observation :: DILI Pos d4T, D4T, SID855856, Zerit Xr, BMY-27857, Stavudine, SID7971664, SID90341632, Zerit
View 224 TAMOXIFEN Human Clinical Blood :: PK :: Cmax Pos 0.06 µg/mL Tamoxifen
View 224 TAMOXIFEN Human Clinical Liver :: observation :: DILI Pos Tamoxifen
View 224 TERFENADINE Human Clinical Blood :: PK :: Cmax Pos 0.5 µg/mL Triludan, SID144203846, Seldane, RMI-9918, SID90341346, SID56422373, SID85231279, Terfenadine, SID26752308, SID855647, Teldane, SID104171258, SID144203847, SID50105228
View 224 TERFENADINE Human Clinical Liver :: observation :: DILI Neg Triludan, SID144203846, Seldane, RMI-9918, SID90341346, SID56422373, SID85231279, Terfenadine, SID26752308, SID855647, Teldane, SID104171258, SID144203847, SID50105228
View 224 TETRACYCLINE Human Clinical Blood :: PK :: Cmax Pos 9.317 µg/mL Cyclopar, Vetquamycin, Panmycin, Achromycin, Liquamycin, E701, Tetracycline, Tetracyn
View 224 TETRACYCLINE Human Clinical Liver :: observation :: DILI Pos Cyclopar, Vetquamycin, Panmycin, Achromycin, Liquamycin, E701, Tetracycline, Tetracyn
View 224 TROGLITAZONE Human Clinical Blood :: PK :: Cmax Pos 2.82 µg/mL Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 224 TROGLITAZONE Human Clinical Liver :: observation :: DILI Pos Rezulin, SID26757864, SID29216382, SID137275811, Gr92132X, SID26755242, Prelay, SID144205672, CS-045, GR-92132X, SID26755243, Troglitazone, CI-991
View 224 WARFARIN Human Clinical Blood :: PK :: Cmax Pos 1.5 µg/mL SID26754489, Jantoven, SID50085958, Warfarin, SID26748308, Coumadin
View 224 WARFARIN Human Clinical Liver :: observation :: DILI Neg SID26754489, Jantoven, SID50085958, Warfarin, SID26748308, Coumadin
View 224 ZALCITABINE Human Clinical Blood :: PK :: Cmax Pos 0.0125 µg/mL Zalcitabine, SID50105404, SID90340765, SID49681781, SID50105405, Dideoxycytidine, Hivid, SID17389522, Ro-24-2027-000, DDC, SID11532889, SID144207040, Ro-242027000
View 224 ZALCITABINE Human Clinical Liver :: observation :: DILI Neg Zalcitabine, SID50105404, SID90340765, SID49681781, SID50105405, Dideoxycytidine, Hivid, SID17389522, Ro-24-2027-000, DDC, SID11532889, SID144207040, Ro-242027000
View 224 ZOMEPIRAC Human Clinical Blood :: PK :: Cmax Pos 2.4 µg/mL Zomepirac, SID26752779, Zomax
View 224 ZOMEPIRAC Human Clinical Liver :: observation :: DILI Neg Zomepirac, SID26752779, Zomax
View 224 CAPTOPRIL Human Clinical Blood :: PK :: Cmax Pos 0.93 µg/mL CAPOTEN, CAPTOPRIL, Capoten, Captopril, Lopril, SQ 14,225, SQ-14225, Tensobon
View 224 CHLORZOXAZONE Human Clinical Blood :: PK :: Cmax Pos 0.457839 µg/mL Strifon Forte Dsc, Parafon Forte, Chlorzoxazone, Parafon Forte Dsc, Paraflex, SID11110946, Parafon, Strifon, Parafon-Forte, SID11110945
View 224 CHLORZOXAZONE Human Clinical Liver :: observation :: DILI Pos Strifon Forte Dsc, Parafon Forte, Chlorzoxazone, Parafon Forte Dsc, Paraflex, SID11110946, Parafon, Strifon, Parafon-Forte, SID11110945
View 224 CIMETIDINE Human Clinical Blood :: PK :: Cmax Pos 1.14 µg/mL SID17389962, Cimetidine, Valmagen, SID104171130, SID11113773, SID90341189, SID26751957, SID50104629, SID460110, SID11533056, SID56462993, Brumetadina, Tagamet HB, SID26747359, Tagamet, Tagamet HB 200
View 224 CIMETIDINE Human Clinical Liver :: observation :: DILI Neg SID17389962, Cimetidine, Valmagen, SID104171130, SID11113773, SID90341189, SID26751957, SID50104629, SID460110, SID11533056, SID56462993, Brumetadina, Tagamet HB, SID26747359, Tagamet, Tagamet HB 200
View 224 DOXYCYCLINE HYCLATE Human Clinical Blood :: PK :: Cmax Pos 5.0 µg/mL ATRIDOX, Alodox, DORYX, DOXY, DOXY 100, DOXY 200, DOXY-LEMMON, DOXYCHEL HYCLATE, DOXYCYCLINE HYCLATE, Doxy-Caps, PERIOSTAT, VIBRAMYCIN, Vibra-Tabs, Vibramycin Hyclate
View 224 DOXYCYCLINE HYCLATE Human Clinical Liver :: observation :: DILI Pos ATRIDOX, Alodox, DORYX, DOXY, DOXY 100, DOXY 200, DOXY-LEMMON, DOXYCHEL HYCLATE, DOXYCYCLINE HYCLATE, Doxy-Caps, PERIOSTAT, VIBRAMYCIN, Vibra-Tabs, Vibramycin Hyclate
View 224 HYDROXYUREA Human Clinical Blood :: PK :: Cmax Pos 60.36 µg/mL SID26747533, SID50106399, Hydroxyurea, Droxia, Hydroxycarbamide, SID11111283, SQ-1089, Hydrea
View 224 HYDROXYUREA Human Clinical Liver :: observation :: DILI Pos SID26747533, SID50106399, Hydroxyurea, Droxia, Hydroxycarbamide, SID11111283, SQ-1089, Hydrea
View 224 TROVAFLOXACIN Human Clinical Blood :: PK :: Cmax Pos 2.09 µg/mL Trovafloxacin, Turvel, Trovan
View 224 TROVAFLOXACIN Human Clinical Liver :: observation :: DILI Pos Trovafloxacin, Turvel, Trovan
View 225 Exemestane 25.0 mg Human Clinical Multiple Organs :: Other :: No Toxicity Progression Free Survival Pos
View 225 Exemestane 25.0 mg
EVEROLIMUS 10.0 mg 		Human Clinical Multiple Organs :: Other :: No Toxicity Progression Free Survival Pos AFINITOR, AFINITOR DISPERZ, CERTICAN, EVEROLIMUS, RAD001, VOTUBIA, ZORTRESS
View 226 LETROZOLE 2.5 mg Human Clinical Multiple Organs :: Other :: No Toxicity Progression Free Survival Pos SID124882709, Femara, CGS-20267, Letrozole, SID11112889
View 226 LETROZOLE 2.5 mg Human Clinical Multiple Organs :: Other :: No Toxicity Progression Free Survival Pos SID124882709, Femara, CGS-20267, Letrozole, SID11112889
View 227 Fulvestrant 500.0 mg Human Clinical Multiple Organs :: Other :: No Toxicity Progression Free Survival Pos
View 227 Fulvestrant 500.0 mg
Palbociclib 125.0 		Human Clinical Multiple Organs :: Other :: No Toxicity Progression Free Survival Pos