NAFLD Disease Overview

Disease Overview Disease Biology Clinical Data Disease Models & Studies
NAFLD Disease State
  • Nonalcoholic fatty liver disease (NAFLD) refers to the entire spectrum of disease, from simple steatosis to NASH to fibrosis/cirrhosis
  • 30% (90 million) people have NAFLD, an abnormally high accumulation of fat within hepatocytes (steatosis)
  • 10% (9 million) NAFLD patients develop inflammation in a condition called non-alcoholic steatohepatitis (NASH), with or without fibrosis
  • 25% (2.5 million) NASH patients develop cirrhosis
  • 200,000 – 500,000 patients at risk to develop hepatocellular carcinoma
NAFLD Overview Image