Diseases

View Disease Clinical Findings Experimental Model Versions Studies Data Points Description
View Alzheimer's Disease 0 0 0 0
View Amyotrophic Lateral Sclerosis 5 0 0 0 ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord.
View Arthritis 7 2 0 0 “Arthritis” is not a single disease; it is an informal way of referring to joint pain or joint disease. Common arthritis joint symptoms include swelling, pain, stiffness and decreased range of motion.
View Asending Infection 0 1 0 0
View Atherosclerosis 3 0 0 0 The build-up of fats, cholesterol, and other substances in and on the artery walls.
View Atrial Fibrillation 0 0 0 0 Atrial fibrillation is an irregular and often rapid heart rate that can increase your risk of stroke, heart failure and other heart-related complications
View Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) 0 0 0 0
View Chemotherapy-Induced Peripheral Neuropathy 0 0 0 0 Peripheral neuropathy known to occur in patients undergoing chemotherapy.
View Coronavirus COVID-19 0 0 0 0 • Coronavirus (COVID-19) is an illness caused by a virus that can spread from person to person. • The virus that causes COVID-19 is a new coronavirus that has spread throughout the world. • COVID-19 symptoms can range from mild (or no symptoms) to severe illness. (Source CDC 2020)
View Diabetes 1 0 0 0 A group of diseases that result in too much sugar in the blood (high blood glucose).
View Ewing's Sarcoma 0 0 0 0 From the Mayo Clinci Website: "Ewing (YOO-ing) sarcoma is a rare type of cancer that occurs in bones or in the soft tissue around the bones. Ewing sarcoma most often begins in the leg bones and in the pelvis, but it can occur in any bone. Less often, it starts in the soft tissues of the chest, abdomen, limbs or other locations." (https://www.mayoclinic.org/diseases-conditions/ewing-sarcoma/symptoms-causes/syc-20351071, http://www.cancerindex.org/geneweb/X0202.htm)
View Glioblastoma multiforme (GBM) 0 0 0 0 Glioblastoma multiforme (GBM) is a highly aggressive and invasive primary brain tumor, originating from glial cells, specifically astrocytes. As a grade IV astrocytoma, GBM represents the most severe classification by the World Health Organization (WHO) for being the leading cause of brain cancer-related death in adults. One of the most striking features of GBM is its highly invasive nature, which allows the cancer cells to infiltrate and destroy surrounding healthy brain tissue rapidly. This extreme aggressiveness, combined with the tumor's complex cellular heterogeneity, makes it exceptionally difficult to treat effectively. Common symptoms include headaches, seizures, cognitive decline, and neurological impairments. Despite advances in surgical intervention, radiotherapy, and chemotherapy, the prognosis remains grim, with a median survival time of approximately 12-15 months. Continued research into the molecular mechanisms driving GBM progression is crucial in developing novel therapeutic strategies against this formidable disease.
View Hutchinson-Gilford Progeria Syndrome 0 0 0 0 Hutchinson-Gilford progeria syndrome (HGPS) is a rare hereditary disorder characterized by premature aging.
View Influenza 0 0 0 0 The flu is a contagious respiratory illness caused by influenza viruses that infect the nose, throat, and sometimes the lungs.
View Insulin resistance 0 0 0 0 Impaired insulin-mediated suppression of glucose production
View Intra-amionic infection 0 0 0 0
View Kidney Injury 0 0 0 0
View Metastatic Breast Cancer 6 0 0 0 Metastatic breast cancer (also called stage IV) is breast cancer that has spread to another part of the body, most commonly the liver, brain, bones, or lungs.
View Metastatic Melanoma 0 0 0 0
View NAFLD 20 1 6 2879 Non-Alcoholic Fatty Liver Disease
View Osteoarthritis 0 0 0 0
View Parkinson's Disease 0 1 0 0 Progressive neurodegenerative movement disorder
View Pediatric Cardiomyopathies 0 0 0 0 Pediatric cardiomyopathy is a rare heart condition that affects infants and children.
View Polycystic Ovary Syndrome 0 0 0 0 Polycystic ovary syndrome (PCOS) is the most common hormonal disorder among women of reproductive age.
View Prostate Cancer 0 1 0 0
View Rheumatoid Arthritis 0 0 0 0
View Stargardt Disease 0 0 0 0 Stargardt disease is a rare genetic eye disease that happens when fatty material builds up on the macula — the small part of the retina needed for sharp, central vision. Vision loss usually starts in childhood — but some people with Stargardt disease don’t start to lose their vision until they’re adults. There’s no treatment for Stargardt disease, but vision rehabilitation can help people make the most of their remaining vision. (NIH: https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/stargardt-disease)
View Tendon Fibrosis 0 0 0 0 Scar-Mediated Fibrovascular Tendon Healing
View Tuberous Sclerosis 5 0 0 0 Tuberous sclerosis complex is a genetic disorder characterized by the growth of numerous noncancerous (benign) tumors in many parts of the body and neurological disorders including epilepsy.
View Type 2 diabetes mellitus (T2DM) 0 0 0 0 Systemic condition where the cells (hepatic, skeletal muscle, and adipose) resist the normal effect of insulin (insulin resistance) during high glucose concentration. In response the beta-cells in the Langerhans/Pancreatic islets respond with high insulin secretion with eventual cell fatigue and failure. The systemic conditions entitle hyperglycemia with hyperinsulinemia,
View Vascular Malformations 6 0 0 0 Vascular malformation is a general term that includes congenital vascular anomalies of only veins, only lymph vessels, both veins and lymph vessels, or both arteries and veins