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Computational |
Computational targets are a specific set of targets (e.g., baseMean, pvalue) resulting from processing data via a computational method or tool (e.g., DESeq2). |
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Compound Level |
Assays intended to assess the concentration of a compound present in media (typically using spectroscopy). |
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Device Characterization |
Assays intended to assess the physical characteristics of the device (e.g., the flow rate). |
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Cell Viability/Proliferation/Toxicity |
Assays intended to assess cell growth and viability. Methods may include labeling and imaging cells. |
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Cell Morphology/Function |
Assays using imaging or video to assess cell shape or cell function, typically using fluorescent labels or dyes. |
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Secreted Protein/Compound |
Assays intended to assess synthesis and transport of proteins (or compounds) out of the cell (typically measured using an ELISA kit). |
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Gene Expression |
Assays intended to assess the extent to which a gene is expressed in a cell to make RNA and proteins. Gene expression may be measured by RNA, protein level, or protein function. (https://ncim.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0017263) |
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Intracellular Biosensor |
Assays in which an expressed protein biosensor is used to monitor intracellular targets. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217087/) |
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Protein Binding |
Assays intended to assess the degree to which substances bind to proteins, typically using rapid equilibrium dialysis (RED) followed by spectroscopy. (https://ncim.nci.nih.gov/ncimbrowser/pages/concept_details.jsf?dictionary=NCI%20Metathesaurus&code=C0033618&type=properties) |