Profiles of a panel of 15 test drugs in the SQL-SAL 1.5 liver model, carried out as a series of 4 studies:
1. EPA1: 3 week study comparing Tolcapone and Entacapone
2. EPA 2: Eighteen day study assessing the the toxicity of Caffeine, Valproic Acid, Thalidomide, and Warfarin.
3. EPA 3: Eighteen day study assessing toxicity of Buspirone, Metoprolol, Methotrexate, and Rifampicin.
4. EPA 4: Eighteen day study assessing toxicity of Erythromycin, Famotidine, Levofloxacin, Rosiglitazone, and Trovafloxacin.
View/Edit | Study Name | Start Date | Study Types | Experimental Models | Model Types | Disease(s) | Data Points | Data Points (omic) | Images | Videos | Plate Maps | Plate Reader Files | Supporting Data Files | Description | Reproducibility Status | Center | Data Entry | Review | Sign Off Date | Data Provider | ID |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
View/Edit | EPA 2 | 2016-09-15 | TOX | SQL-SAL 1.5 | Fluidic-3D | -No Diseases- | 343 | 0 | 0 | 0 | 0 | 0 | 0 | Eighteen day study assessing the the toxicity of Caffeine, Valproic Acid, Thalidomide, and Warfarin. | UPDDI | Dillon Gavlock | 4 | 2019-07-16 | Taylor_EPA | 120 | |
View/Edit | EPA 3 | 2016-09-29 | TOX | SQL-SAL 1.5 | Fluidic-3D | -No Diseases- | 345 | 0 | 0 | 0 | 0 | 0 | 0 | Eighteen day study assessing toxicity of Buspirone, Metoprolo, Methotrexate, and Rifampicin. | UPDDI | Dillon Gavlock | 4 | 2019-07-16 | Taylor_EPA | 121 | |
View/Edit | EPA 4 | 2016-10-13 | TOX | SQL-SAL 1.5 | Fluidic-3D | -No Diseases- | 356 | 0 | 0 | 0 | 0 | 0 | 0 | Eighteen day study assessing toxicity of Erythromycin, Famotidine, Levofloxacin, Rosglitazone, and Trovafloxcin. | UPDDI | Dillon Gavlock | 4 | 2019-07-16 | Taylor_EPA | 122 | |
View/Edit | EPA 1 | 2016-08-04 | TOX | SQL-SAL 1.5 | Fluidic-3D | -No Diseases- | 256 | 0 | 0 | 0 | 0 | 0 | 0 | 3 week study comparing Tolcapone and Entacapone | UPDDI | Albert Gough | 4 | 2019-08-06 | Taylor_EPA | 117 |